David Alexander Muller

Efficient delivery of mRNA-LNPs in primary and secondary liver cancer

This study shows that mRNA-LNPs can efficiently deliver mRNA to hepatocytes in healthy and diseased livers, including tumors, suggesting potential for systemic mRNA therapy in liver cancer.

Vaccine-induced and hybrid immunity against SARS-CoV-2 variants of concern in two cohorts in Queensland, Australia (2021-2022).

The paper evaluates vaccine-induced and hybrid immunity against SARS-CoV-2 variants in two cohorts, finding reduced antibody titres and neutralization activity against Omicron variants, with some recovery after multiple vaccinations.

Integrating 12 Spatial and Single Cell Technologies to Characterise Tumour Neighbourhoods and Cellular Interactions in three Skin Cancer Types

The paper integrates 12 spatial and single-cell technologies to analyze cellular interactions and signatures in three skin cancers, identifying key therapeutic targets and genetic associations.