C. elegans

This study shows dietary HSP90 extends C. elegans lifespan and healthspan via extracellular signaling, and combines it with a senolytic inhibitor for enhanced longevity.

The paper develops a C. elegans model to visualize subcellular architecture across adult life and identifies a midlife architectural state shift linked to aging and homeostatic challenges.

The paper investigates IFT-A-IFT-B coordination in cilia using multiple techniques and finds that BBSome-IFT proximities are essential for their coupling.

The paper shows that Wnt proteins, receptors, and Dvl localize asymmetrically in C. elegans seam cells, linking Wnt gradients to cell polarity through positive feedback.

The paper identifies Sgl{varphi}Cb5 as targeting MraY and shows convergent evolution between ssRNA and ssDNA phage Sgls.

This study shows increasing PCAF-1 in C. elegans extends lifespan, preserves healthspan, and enhances stress responses by reprogramming transcription and improving proteostasis.

This study measures torque and stator dynamics in Campylobacter jejuni flagellar motor, revealing distinct behavior compared to model organisms.

The paper develops GG-Clock, an image-based aging clock using germ granule remodeling in C. elegans, showing it predicts age and responds to fasting.

This paper uses adaptive laboratory evolution to improve C. necator biofilm formation on cathodes for microbial electrosynthesis, identifying a mutation that accelerates biofilm development.

This study identifies male-specific genome sequences for non-invasive sex identification in Nishikigoi, develops PCR markers, and establishes a field-applicable diagnostic platform.

This paper uses oyster genomics to identify genomic regions associated with size and immune response, highlighting genome structure's role in environmental adaptation and health.

The paper shows that glutamate and neuropeptide signaling in C. elegans males convert brief mate contact into a persistent search behavior.

The paper identifies host genes in C. elegans required for bacterial adherence to the gut epithelium using a genetic screen.

This study identifies Scs7 as a key regulator of fungal pathogenicity and drug susceptibility in Candida albicans, showing resveratrol inhibits Scs7 and enhances antifungal efficacy.

The paper identifies structural determinants in TrxA that confer its essentiality in Synechocystis, showing that its function cannot be replaced by other thioredoxins despite similar abundance.

The paper shows that anisotropic lateral surface tension, mediated by HMR-1/E-cadherin, directs invagination in C. elegans gastrulation, complementing apical constriction.

This study identifies fss genes that regulate stalked cell morphogenesis and cell cycle progression independently of the flagellum in Caulobacter crescentus.

The paper introduces LADD to measure lineage path deviations from inferred developmental dynamics in single-cell RNA-seq data and finds lineages move faster than optimal paths.

This study identifies GABAergic and cholinergic signaling disruptions as key mechanisms of cisplatin-induced sensory dysfunction in NER-defective C. elegans.

The paper identifies the CCAAT-binding complex (CBC) as a key regulator that overrides genetic sterility in Candida albicans by integrating environmental stress signals to enable mating.

The paper shows that dystrophic muscle has an elevated precontractile calcium set point sustained by limited PMCA1 export in C. elegans and human myoblasts.

The paper updates a toolkit for genetic studies in C. briggsae by identifying indel variants and mapping mutations to genes using high-throughput sequencing.

The paper investigates how gene expression influences genome-wide mutation rates in Drosophila melanogaster and Caenorhabditis elegans, finding that highly expressed genes have lower mutation rates due to transcription-coupled repair.

This study uses advanced microscopy to show that myosin II minifilaments persist and recycle in C. elegans embryos, contributing to cortical contractility through stable, static interactions with actin.

The paper shows that Pseudomonas fluorescens protects Chlamydomonas reinhardtii from Pseudomonas protegens by inactivating its toxin protegencin in a tripartite microbial interaction.

The paper identifies oleate depletion as a metabolic signal sensed by C. elegans to activate innate immunity against bacterial infection.

The paper introduces the C. elegans Connectome Toolbox, a framework for integrating and analyzing multimodal connectomic data, enabling comparison across datasets and modalities.

The paper quantifies developmental variation in C. elegans natural populations using embGAN, finding genotype-specific differences in cell-cycle timing that exceed within-strain variation.

This study shows that temperature affects Culex tarsalis vector competence, tissue bottlenecks, and gene expression in response to West Nile virus infection.

This study compares the susceptibility and molecular responses of three nematode species to the nematode-trapping fungus Arthrobotrys oligospora, revealing species-specific differences in behavior and gene expression.