Xenopus

The paper investigates how Aurora B kinase disassembles actin and keratin networks at the midplane of cleaving Xenopus laevis eggs, facilitating cytokinesis.

The paper demonstrates that lipid membranes can organize both microtubules and actin, even when one cytoskeletal system is paralyzed, revealing a universal principle of cytoplasmic self-organization.

The paper identifies a new NAT family member, Slc23a5, in fish and amphibians, clarifies its evolutionary relationships, and suggests uric acid as its preferred substrate.

This paper introduces a photoactivatable tool to disrupt keratin intermediate filaments and shows its role in morphogenetic movements during Xenopus embryogenesis.

This study identifies the apical membrane localization of VSP in kidney tubule epithelial cells and characterizes the functional differences between Xl-VSP1 and Xl-VSP2.

This study shows CCDC11 is essential for cytokinesis and cell-cell adhesion via RhoA regulation, linking it to heterotaxy disease pathogenesis.

This paper introduces a photoacoustic pigment relocalization sensor inspired by cuttlefish chromatophore cells to detect GPCR-mediated signaling molecules in vitro and in vivo.

The paper shows mitotic CDK promotes replisome disassembly, fork breakage, and complex DNA rearrangements via TRAIP-dependent ubiquitylation of CMG helicase.

This study uses bone structure analysis to infer the lifestyles of extinct xenarthrans by comparing them to extant species.

This study decouples the roles of cell shape and mechanical stress in epithelial mitosis orientation and rate using Xenopus laevis tissue.

This study identifies calcium nanodomains associated with spindles in Xenopus eggs, embryos, and HeLa cells, showing their essential role in spindle assembly and stability.

This study compares two frog antimicrobial peptides, temporin L and aurein 2.5, to understand their differing antibacterial activities despite similar structures.

This study examines how mechanical heterogeneity and parallel microtubule arrays influence meiotic spindle length and stability in Xenopus egg extracts.

The paper shows that the CMG helicase bypasses DNA-protein cross-links without prior proteolysis, and RTEL1 aids this process and also promotes proteolysis.

The paper identifies extreme nuclear branching in healthy Xenopus tail fin epidermal cells and shows its disruption affects fin morphology.

The paper investigates how vocal signal production changed in secondary aquatic frogs, finding that sound is generated by laryngeal resonance modes rather than cavitation, with species-specific frequency ratios aiding species identification.

This paper shows that the pyriproxyfen metabolite 4’OH-pyriproxyfen disrupts thyroid hormone signaling and increases Musashi-1 levels in neuroprogenitors, potentially enhancing Zika virus replication.

This study shows that CDK phosphorylation of M18BP1 enables its metaphase centromere localization via CENP-C binding, which is critical for proper CENP-A nucleosome assembly.

This study shows 14-3-3 proteins regulate keratin intermediate filament reorganization at cell-cell contacts in Xenopus embryos.

This paper describes methods to express and purify functional GABAA receptors for structural studies, identifying a minimal construct that retains agonist binding activity.

The paper shows PLK4 self-assembles into structures that recruit tubulin and form de novo MTOCs in Xenopus extracts.

This study examines the cardiac toxicity of PAHs in Xenopus laevis, finding that PHE, PYR, and FLA impair cardiac function and increase cyp1a expression, while BaP effects are AHR-dependent.

This study identifies CDC20B as essential for deuterosome-mediated centriole production in multiciliated cells, showing its interaction with PLK1 and Separase.

The paper demonstrates that tensile forces from convergent thickening and extension drive blastopore closure in Xenopus, with CT alone sufficient for closure in ventralized embryos.

The paper re-examines the functional properties of NPF6.3/NRT1.1/CHL1 in Xenopus oocytes, finding it acts as a non-electrogenic, low-affinity nitrate transporter, with internal nitrate regulation involving the P492 residue.

The paper analyzes neuropeptide complements in xenacoelomorphs to infer ancestral bilaterian systems and their evolutionary correlation with nervous system architecture.

The paper compares spindle assembly in egg extracts of Xenopus borealis with Xenopus laevis and Xenopus tropicalis, finding size scaling differences and shared scaling phenomena.

The persistence of hybrid ancestry is predictable from local recombination rates in three replicate hybrid populations and in humans.

This paper introduces M2-seq, a method to infer RNA structures through chemical mapping and mutations, achieving accurate helix detection with low false positives in vitro and in complex biological environments.