Mosquito-borne diseases and control

The paper examines how waterbird species' functional diversity and traits correlate with Japanese encephalitis virus (JEV) landscape distribution across Australia and the Central Indo-Pacific region.

This paper identifies the alphavirus TF protein's role in promoting viral propagation by altering cell-cell boundaries through downregulation of Scribble.

This study investigates how myeloid cell activation during ZIKV encephalitis correlates with recovery of cortical functional connectivity in mice.

This paper isolates and characterizes circular viral copy DNA (cvcDNA) from DENV-2 infected mosquito cells and shows it can reduce DENV-2 replication.

This paper develops two Fc-modified human monoclonal antibodies that neutralize all dengue virus serotypes without causing antibody-dependent enhancement or complement activation.

This study shows that K+ channel inhibitors reduce SFV replication and cytotoxicity in vitro by disrupting an early post-entry step, suggesting potential for antiviral repurposing.

The study identifies two unique amino acid substitutions in Brazilian YFV strains that may reduce vaccine effectiveness by altering epitope binding.

This study uses cryogenic-electron microscopy to characterize late-stage Chikungunya virus replication organelles in human cells, revealing their structural heterogeneity and dynamic roles in viral replication and protein production.

This study evaluates the vector competence of Aedes aegypti and Culex quinquefasciatus mosquitoes for Mayaro virus using a mice model, finding Ae. aegypti highly competent and Cx. quinquefasciatus less so.

The paper identifies human miRNAs that interact with dengue virus proteins and proposes a therapeutic strategy based on miRNA regulation.

The paper detects and sequences Japanese encephalitis virus genotype III strains from pig and mosquito in Assam, India, revealing genetic polymorphisms and phylogenetic relationships with Chinese strains.

The paper was withdrawn due to lack of full author consent and is not intended for citation.

The paper characterizes Chikungunya virus outbreaks in Brazil's southernmost state, identifying lineage changes and transmission dynamics from 2017 to 2021.

This study shows ZIKV alters metabolism in different fetal neuronal progenitors, potentially affecting neurodevelopment during early pregnancy.

This paper demonstrates that ex vivo midgut cultures of Aedes aegypti mosquitoes can be efficiently infected by mosquito-borne alpha- and flaviviruses and used to test antiviral compounds.

The paper performs an RNAi screen to identify host genes involved in Dengue virus infection, finding 1,730 genes that inhibit infection and 194 that enhance it, and identifies a common gene signature across multiple screens.

This study identifies Dhx15 as a host factor that controls glycolysis and arbovirus replication in Aedes aegypti cells by modulating gene expression.

The paper examines plasma ceramide levels in dengue patients and finds higher ceramides in severe cases, with negative correlations to platelet count and hematocrit during recovery.

This paper investigates how ZIKV NS4A interacts with host ANKLE2 to promote viral replication and disrupt neurodevelopment.

This study assesses the vector competence of Aedes aegypti for Ebinur Lake virus (EBIV) and identifies transcriptional changes in mosquitoes infected with the virus.

This study examines genetic and microbial diversity of Culex tritaeniorhynchus across multiple continents, finding high genetic and microbial variation and evidence of Wolbachia and insect-specific viruses.

The paper reveals novel molecular mechanisms of alphavirus nsP2 protease and predicts human proteins cleaved by these proteases, suggesting broader roles in viral arthritis pathogenesis.

The paper describes a rapid surveillance response and genome sequencing of a new Yellow Fever Virus sublineage in Minas Gerais, Brazil, in 2021, revealing its relation to a 2017 Amazon lineage.

The paper investigates NPC2 proteins in Aedes aegypti, identifying potential sterol and fatty acid-binding proteins and analyzing their expression changes in virus-infected tissues.

The paper identifies and validates 106 miRNAs in Culex tarsalis mosquitoes using small RNA sequencing and experimental validation.

The paper identifies Japanese Encephalitis Virus genotype V and other arboviruses in mosquitoes from Camp Humphreys using metagenomic analysis, showing the virus is circulating in South Korea.

This paper develops a CRISPR-based sterile insect technique to eliminate Aedes aegypti mosquitoes in controlled environments.

This study develops a model to predict Dengue Fever cases in Brazilian cities one month ahead, finding that random forests with historical data yield the lowest errors.

This study investigates how DENV2C chaperone activity facilitates strand displacement during RNA rearrangement without altering the structural functionality of the cHP hairpin element.

The paper reports genetic evidence of West Nile virus circulation in horses and a human case in Brazil, highlighting the need for active surveillance.