Nutrition and Health in Aging

Systemic drivers and molecular mechanisms of sarcopenia in aetiology-specific end-stage liver disease

This study identifies aetiology-specific molecular mechanisms of sarcopenia in end-stage liver disease by analyzing transcriptomic changes and cytokine profiles in muscle and plasma.

Sex Differences in Cachexia Outcomes and Branched-Chain Amino Acid Metabolism Following Chemotherapy in Aged Mice

This study investigates sex differences in cachexia outcomes and BCAA metabolism in aged mice following chemotherapy, finding that males experience worse muscle damage and altered BCAA levels compared to females.

Sex-specific survival but not tissue wasting in the KPP mouse model of pancreatic cancer-induced cachexia

Early adipose tissue wasting in a novel preclinical model of human lung cancer cachexia

This study develops a novel mouse model of human lung cancer cachexia that exhibits early adipose tissue wasting and metabolic reprogramming, mirroring human disease features.

Haptoglobin and glutamine synthetase may biomark cachexia induced by anti-acute myeloid leukemia chemotherapy

This study shows that the AML chemotherapy regimen induces cachexia in mice, characterized by body and lean mass loss, and identifies haptoglobin as a potential biomarker for chemotherapy-induced cachexia.

CHANGES IN MUSCLE QUALITY FOLLOWING SHORT-TERM RESISTANCE TRAINING IN OLDER ADULTS: A COMPARISON OF ECHO INTENSITY AND TEXTURE ANALYSIS

This study examines changes in muscle quality after resistance training in older adults, finding that echo intensity improved but texture analysis did not detect significant changes.

In silico Investigation of Molecular Networks Linking Gastrointestinal Diseases, Malnutrition, and Sarcopenia

The paper constructs a knowledge base of molecular interactions linking gastrointestinal diseases, malnutrition, and sarcopenia and provides an interactive tool for in silico analysis.

Predicting the risk of sarcopenia in elderly patients with patellar fracture: Development and assessment of a new predictive nomogram

This paper develops a predictive nomogram to assess sarcopenia risk in elderly patellar fracture patients using logistic regression and Lasso analysis, showing good predictive performance.

Clinical correlates of sarcopenia and falls in Parkinson's disease

This study examines sarcopenia and fall risk in Parkinson's disease patients, finding associations between sarcopenia, clinical factors, and fall history.