Neurobiology and Insect Physiology Research

This paper uses optimization-based modeling to study how sensory networks, specifically in the olfactory system, track low-dimensional latent representations of stimuli through temporal dynamics.

The paper investigates the role of GGN neurons in locust olfactory circuits, showing they extend the dynamic range of Kenyon cells and suggest a new olfactory pathway.

The paper shows that inhibiting programmed cell death in Drosophila olfactory neurons generates functional 'undead' neurons that integrate into circuits and contribute to evolutionary differences in carbon dioxide sensing.

This study identifies Dilp2 as essential for regulating sleep depth in response to starvation, revealing distinct mechanisms for sleep duration and depth homeostasis in Drosophila.

The paper identifies a quiescent state in C. elegans, PRQ, which is enhanced by cellular stress and involves neuropeptidergic mechanisms but is not sleep.

The paper shows non-heritable variation in neural circuit development causes individual differences in behavior using Drosophila.

This study identifies molecular and neuronal changes underlying behavioural divergence in Drosophila sechellia through mutational analysis and calcium imaging.

The paper investigates how alcohol affects transcription and RNA processing in Drosophila mushroom body neurons, identifying lasting transcript changes associated with ethanol exposure.

The paper challenges the view that hemiellipsoid bodies are a derived crustacean trait and shows mushroom bodies exist in lineages predating Reptantia.

The paper investigates how cellular and circuit mechanisms transform dense to sparse odor representations in the insect olfactory system, identifying spike-frequency adaptation and lateral inhibition as key factors.

This study investigates how GABA and insulin signaling in Drosophila larval olfactory sensory neurons modulate olfactory behavior during starvation.

The paper identifies neurons and brain regions in Drosophila larvae that influence sensorimotor decisions and sequence transitions in response to mechanosensory stimuli.

The paper identifies genetic factors influencing basal and induced activity levels in Drosophila melanogaster using a genetic reference panel and exercise assays.

The paper uses RNA-Seq to analyze neuromodulatory gene expression in the antennae of Rhodnius prolixus, identifying new genes and suggesting local regulation of sensory function.

This study provides a detailed brain atlas of the Australian Bogong moth, revealing no major structural specializations linked to its migratory behavior.

This study identifies specific mushroom body output neurons that inhibit proboscis extension and feeding behavior in Drosophila when activated.

The paper examines visual pathways in the jumping spider Marpissa muscosa, finding similarities and differences in principal and secondary eye connectivity compared to Cupiennius salei.

This study shows that impaired EAT-4 vesicular glutamate transporters in C. elegans lead to defective thermal avoidance behavior, highlighting the role of glutamate signaling in nocifensive responses to noxious heat.

The paper uses transcriptomics to show that pleuropodia in locust embryos express enzymes for cuticle degradation and immunity, supporting their role in hatching and immune defense.

The paper characterizes gene expression in 67 Drosophila visual system cell types using TAPIN-seq and genetic drivers, building a transcriptome resource to study neural circuit function.

This study shows that long-term neuronal activity in C. elegans URX sensory neurons leads to dendritic branch elaboration, independent of oxygen sensitivity.

This study shows environmental light is essential for long-term memory maintenance in Drosophila by activating CREB in mushroom bodies via the Pdf signaling pathway.

The paper investigates how presynaptic developmental plasticity enables sparse wiring of Drosophila mushroom body Kenyon cells, ensuring functional robustness despite reduced cellular diversity.

This study shows that the strength of the JON-GF synapse in Drosophila remains constant with age, while JON sensitivity changes, affecting GF sensitivity.

FreeClimber quantifies climbing velocity for Drosophila cohorts, eliminating systematic biases of manual methods through automated and high-throughput analysis.

The paper investigates olfactory coding in the American cockroach, showing stimulus-specific, concentration-dependent responses and spatial structure preservation in odorant detection.

The paper identifies two chromatic encoding pathways in Drosophila photoreceptors, including a horizontal-cell-mediated pathway that expands chromatic encoding through lateral inhibition.

This study identifies Drosulfakinin as a regulator of social isolation-induced aggression in Drosophila, showing a U-shaped relationship between Dsk signaling and aggressive behavior.

This study shows that E93 depletion in cockroaches prevents prothoracic gland histolysis, allowing adults to molt again, supporting the role of E93 in metamorphosis.

The paper profiles cell-surface proteomes in Drosophila olfactory neurons across development, identifying new regulators of neural circuit assembly.