Advanced Neuroimaging Techniques and Applications

The paper investigates age-related changes in cortical myeloarchitecture during adolescence using longitudinal MRI data and identifies two distinct developmental processes.

The paper examines white matter changes after unilateral visual cortex resection in children, finding preserved contralesional connectivity in most cases.

The paper identifies two distinct fiber pathways connecting the amygdala and prefrontal cortex in humans and monkeys using diffusion imaging.

The paper compares white matter connectivity in individuals with and without family history of alcohol use disorders using connectometry, finding reduced connectivity in specific brain regions in the FH+ group.

This study uses diffusion MRI to show short-term structural brain plasticity after motor sequence learning, revealing dynamic changes in motor regions like the premotor cortex and cerebellum.

The paper develops a free water (FW) processing pipeline to differentiate mild cognitive impairment (MCI) and Alzheimer's disease (AD) from controls using diffusion MRI data.

This study shows that limbic white matter microstructure and hippocampal subfield volumes together predict verbal learning rates in older adults, with an interaction effect observed.

This paper introduces a method for fetal diffusion MRI reconstruction with intensity correction, enabling detailed analysis of brain connectivity and microstructure in-utero.

The paper investigates microstructural changes in the visual cortex during childhood and finds that apparent thinning is due to increased myelination rather than pruning.

This paper estimates axon conduction velocity in vivo from MRI parameters, showing that 89.2% of variance is explained by axon diameter and g-ratio, with accurate estimates achievable under certain parameter bounds.

This study finds that higher HbA1c levels are associated with worse cognitive performance and reduced white matter integrity in healthy young adults.

MRtrix3 provides an open-source C++11 and Python software framework, command-line suite, and OpenGL 3.3 viewer for fast multi-dimensional medical image processing and diffusion MRI analysis.

This paper introduces differential tractography to detect neuronal injury by comparing repeat MRI scans and shows its clinical relevance in multiple neurological conditions.

This study examines age-related changes in cortical morphometry and white matter microstructure using partial least squares correlation, finding a coupled relationship between frontal and parietal grey matter and underlying white matter.

The paper shows that high b-value diffusion tensor imaging (DTI) metrics are strongly associated with NODDI metrics in cortical gray matter, but low b-value DTI does not accurately reflect microstructure.

This study assesses white matter alterations in Parkinson’s disease using diffusion tractography and age-specific anatomical atlases, finding decreased fractional anisotropy in specific brain connections.

The paper identifies shared and segregated white matter tracts for math and reading networks using multimodal MRI, revealing structural differences related to myelination in sub-bundles.

This paper introduces REDIM, a method to compute joint moments of relaxation-diffusion to characterize neural microstructure, showing it can distinguish fiber bundles with similar orientations but different relaxation rates.

This study shows that aging reduces white matter integrity and BOLD modulation, which together impair cognitive performance and executive function.

The paper provides normative cortical thickness values for human visual areas using FreeSurfer data from 960 participants, showing systematic variation aligned with visual system hierarchies and normal distribution patterns.

The paper quantifies microstructural changes in normal-appearing white matter near white matter hyperintensities in older adults, showing spatial gradients of damage linked to WMH burden.

This study uses high angular resolution diffusion MRI to compare developmental programs of cortical pathways in human and mouse brains, finding conserved and deviant patterns in radial glial and corpus callosum development.

The paper validates per-bundle dMRI metrics in a fiber crossing region using histological data from axonally degenerated optic nerves in rats.

This study uses non-negative matrix factorisation to identify cortical regions co-varying with connectivity subnetworks in children and adolescents, finding age-related changes in cortical thickness and connectivity.

This paper proposes a joint model for diffusion MRI and microscopy data to improve microstructural analysis by combining complementary information from both modalities.

This study uses MRI-measured g-ratio to predict conduction delays in the corpus callosum and finds age-related differences in motor fibers.

The paper examines the relationship between white matter microstructure and longitudinal depressive symptoms in mid-late life, finding significant associations across different measures of symptomatology.

This paper reduces the dimensionality of diffusion MRI measures to identify biologically interpretable components that capture age-related changes in white matter microstructure.

This paper quantifies uncertainty in MAP-MRI derived metrics using residual bootstrap methods, showing that resampling within each shell generates larger uncertainty than using all shells.

This paper introduces diffusion profile realignment to reduce variability in along-tract dMRI analysis by improving alignment across subjects, enhancing detection of regional changes.