Photoreceptor and optogenetics research

Optical inhibition of zebrafish behavior with anion channelrhodopsins

This study tests the use of GtACR1 and GtACR2 anion channelrhodopsins in zebrafish to optically inhibit neurons and assess neural circuit necessity.

Anion-conducting channelrhodopsins with tuned spectra and modified kinetics engineered for optogenetic manipulation of behavior

The paper engineers anion-conducting channelrhodopsins with tunable spectra and kinetics for optogenetic control of behavior.

Dynamic blue light-inducible T7 RNA polymerases (Opto-T7RNAPs) for precise spatiotemporal gene expression control

The paper develops blue light-inducible T7 RNA polymerases for precise spatiotemporal control of gene expression in bacteria and other organisms.

Skin photoreceptors in the leopard frog

The paper explores the evolutionary origins of vertebrate sense organs by examining the relationship between skin receptors and specialized sensory structures.

High Current Optogenetic Channels For Stimulation And Inhibition Of Primary Rat Cortical Neurons

The paper demonstrates the use of ChR2-XXL and GtACR1 in primary rat cortical neurons to manipulate neuronal firing patterns through high current optogenetic channels.

A two-state photoconversion model predicts the spectral response dynamics of optogenetic systems

The paper develops a two-state photoconversion model to predict and program gene expression dynamics in optogenetic systems with high accuracy.

SkinnerTrax: high-throughput behavior-dependent optogenetic stimulation of Drosophila

SkinnerTrax enables high-throughput, behavior-dependent optogenetic stimulation of Drosophila using simple and inexpensive components.

Potent optogenetic inhibition of behavior with anion channelrhodopsins

The paper demonstrates that anion channelrhodopsins can effectively inhibit various behaviors in Drosophila, highlighting their utility in circuit analysis.

Dynamically controlled light delivery over large brain volumes through tapered optical fibers

This paper introduces tapered optical fibers for dynamic light delivery in brain regions, showing they can illuminate large volumes or specific subregions with adjustable precision.