Morphological variations and asymmetry

3D morphometric analysis of mouse skulls using microcomputed tomography and computer vision

The paper analyzes mouse skull morphology using microCT and computer vision to compare wildtype and transgenic strains, finding limited morphological differences and significant dorsal bone thickness variations.

The Genetic Architecture of Morphological Scaling

The paper investigates the genetic architecture of morphological scaling in Drosophila by analyzing variation in scaling relationships across isogenic lineages under different nutritional conditions.

MusMorph, a database of standardized mouse morphology data for morphometric meta-analyses

MusMorph provides standardized mouse morphology data for meta-analyses, including craniofacial and brain structures across developmental stages and genotypes.

A method for morphological feature extraction based on variational auto-encoder : an application to mandible shape

The paper introduces Morpho-VAE, a landmark-free method for shape analysis using variational autoencoders, applied to primate mandible images to extract morphological features for classification.

Computational anatomy and geometric shape analysis enables analysis of complex craniofacial phenotypes in zebrafish mutants

This paper uses computational anatomy to quantify 3D craniofacial phenotypes in zebrafish mutants, identifying shape differences in bmp1a mutants.

Testing the accuracy of 3D automatic landmarking via genome-wide association studies

This study evaluates the accuracy of 3D automatic landmarking by comparing its ability to detect QTLs in mouse skulls and jaws with a semi-automatic method.

Shapes and Genescapes: Mapping Multivariate Phenotype-Biological Process Associations for Craniofacial Shape

The paper develops a process-centered multivariate genotype-phenotype approach to analyze craniofacial shape variation in mice, linking gene sets to shape axes and predicting phenotypic effects beyond shape.

Size and shape regional differentiation during the development of the spine in the nine-banded armadillo (Dasypus novemcinctus)

This study examines the ontogenetic development of the spine in nine-banded armadillos, identifying regional differentiation in size and shape during vertebral growth.

Complex genetic architecture of three-dimensional craniofacial shape variation in domestic pigeons

The paper identifies genetic loci associated with craniofacial shape variation in domestic pigeons using quantitative trait locus scans and multi-locus modeling.

A ROR2 coding variant is associated with craniofacial variation in domestic pigeons

The paper identifies a ROR2 coding variant associated with short beak morphology in domestic pigeons, linking it to craniofacial variation through QTL mapping and genomic analysis.

Global Constraints within the Developmental Program of the Drosophila Wing

The paper quantifies phenotypic variation in Drosophila wings and identifies a constrained developmental program that integrates genetic and environmental inputs into a single morphological axis.

A Statistical Pipeline for Identifying Physical Features that Differentiate Classes of 3D Shapes

This paper introduces SINATRA, a statistical pipeline for identifying physical features differentiating 3D shape classes without requiring correspondences, and demonstrates its application to primate mandibular molars.

Knocking-out the human face genes TBX15 and PAX1 in mice alters facial and other physical morphology

This paper shows that knocking out TBX15 and PAX1 in mice alters facial and physical morphology, supporting their role in human facial development.

Application of high-resolution landmark-free morphometrics to a mouse model of Down Syndrome reveals a tightly localised cranial phenotype

This paper applies a landmark-free morphometric method to a mouse model of Down syndrome, revealing localized cranial phenotypes not detectable with traditional landmark-based approaches.

A model of developmental canalization, applied to human cranial form

The paper develops a statistical model to estimate developmental canalization from longitudinal phenotypic data and applies it to human craniofacial morphology, finding strong canalization in craniofacial size and nasopharynx dimensions but not in frontal sinus size.

Facial shape and allometry quantitative trait locus intervals in the Diversity Outbred mouse are enriched for known skeletal and facial development genes

This study identifies 37 QTL for facial shape in DO mice, finding enrichment for genes involved in skeletal and facial development, despite small individual effects.

Isolating and Quantifying the Role of Developmental Noise in Generating Phenotypic Variation

The paper distinguishes the contribution of developmental noise from genotype and environment to phenotypic variation in leopard gecko head color patterns using mathematical simulations.

Quantitative morphological variation in the developing Drosophila wing

The paper quantifies morphological variation in Drosophila wing development across stages and links early morphology to adult traits.

Development and assessment of fully automated and globally transitive geometric morphometric methods, with application to a biological comparative dataset with high interspecific variation

The paper evaluates and improves automated geometric morphometric methods for shape analysis, showing enhanced accuracy and taxonomic distinctiveness compared to existing approaches.

Patternize: An R Package For Quantifying Color Pattern Variation

patternize quantifies color pattern variation across organisms using image alignment and segmentation, enabling comparison and analysis through PCA and heatmaps.