Discover, rate, and discuss biology preprints.

This paper isolates and characterizes bacterial strains for accelerating lime mortar carbonation, finding that S. patagoniensis produces the most CO2 and achieves faster and greater carbonation.

This paper introduces squeezed light field microscopy (SLIM), a method for high-speed 3D volumetric imaging, and demonstrates its application in tracking blood cell motion and neural activity in vivo.

This study develops a microfluidic model of atherosclerosis that mimics dynamic arterial narrowing and tests drug effects on endothelial cell junctions.

This paper introduces an algorithm to reconstruct 3D molecular orientation and density from polarized fluorescence microscopy data, demonstrating its application on biological structures and dynamics.

This paper develops a gene delivery vector based on a human anellovirus, demonstrating transduction in multiple tissues and durable in vivo function in mice.

This paper introduces a method for high-plex fluorescent imaging using DNA strand displacement without fluidic exchange, achieving 25-plex RNA imaging in fixed cells.

The paper develops a poroelastic model to show that the interaction between fluid velocity and pore pressure, not their individual effects, drives load-induced bone formation in mouse tibiae.

This paper introduces RNA-stabilized coat proteins for low-background live-cell RNA imaging, enabling sensitive visualization of single mRNAs and dual-color imaging of distinct RNA species.

This paper introduces a post-processing framework to improve real-time sleep staging reliability in neuromodulation by combining smoothing techniques and control logic.

This paper develops a DNA nanostructure platform for ultrasensitive HIV-1 detection and antiviral activity, showing improved binding affinity and diagnostic performance.

This study develops a microfluidic device to enrich pancreatic cancer-derived extracellular vesicles based on charge, linking KRAS status to EV secretion and surface charge.

The paper describes a microfluidic system for efficient purification of minicells used in cancer therapy.

NeuroTest evaluates sensing-capable electrophysiology and neurostimulation systems through a low-cost, open-source benchtop platform to standardize testing and reduce variability across institutions.

This paper introduces TomoSAXS to map fibril-to-fibre mechanics in intervertebral discs and shows how pre-strain and strain variability correlate with mechanical behavior.

The paper uses a musculoskeletal model to study how the number and maximum firing rate of motor units affect reaching performance in human upper limb movements.

This study evaluates YOLOv11 for detecting and classifying red blood cell morphologies using synthetic datasets to address data scarcity and cross-dataset bias.

The paper develops a 3D MASH liver fibrosis model using patient-derived organoids and shows that YAP1 knockdown reduces fibrosis by inducing myofibroblast senescence.

The paper introduces ICNet, a deep learning model that accurately simulates neural dynamics in the auditory midbrain across various sounds, including speech.

This paper designs switchable cytokines that are activated by Venetoclax, showing tumor control comparable to native cytokines and enhancing therapeutic safety.

This study introduces magnetic bioprinting to control tissue geometry and mechanical forces in skeletal muscle, enabling shape fabrication and mechanical property investigation.