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This paper shows that Prox1 acts as a mitotic bookmark in mouse hippocampal neural stem cells to preserve neuronal lineage identity by promoting H3K27me3 restoration.

This study identifies Kindlin-2-Moesin interaction as a regulator of sprouting angiogenesis by modulating endothelial membrane tension and VEGF signaling.

This study investigates the synergistic roles of TNAP and PHOSPHO1 in postnatal bone mineralisation using a novel murine knockout model, revealing their critical function in biomineralisation and skeletal development.

The paper examines whether spinal cord regeneration in adult zebrafish recapitulates embryonic development by analyzing single-cell RNA-seq data across development, homeostasis, and regeneration.

The paper compares the gene regulatory network of compound eye development between Drosophila and Episyrphus balteatus, finding conserved and species-specific regulatory interactions.

This study shows that RPA1 is critical for DNA damage repair in oocytes, leading to infertility when disrupted.

The paper reconstitutes planar polarity initiation in an engineered epithelial system, showing collective migration breaks symmetry and drives polarity across scales.

This study shows that Wnt11 and core PCP components interact reciprocally to establish cell polarity in Xenopus embryos without relying on Wnt gradients.

This paper introduces Airy beam light sheet microscopy to image subcellular dynamics in large tissues with high spatial and temporal resolution across multiple organisms and biological processes.

The paper introduces LS-MPRA and d-MPRA methods to map gene-specific regulatory regions at single nucleotide resolution, identifying known and novel CRMs in retinal and progenitor cells.

This paper introduces UTMM, a method to simultaneously measure transcriptomes and mechanical properties in intact embryos, revealing coupling between RNA expression and intracellular compliance during early development.

LineageMap infers spatially resolved cell lineage trees from tri-modal single-cell data, outperforming existing methods in accuracy and revealing biologically coherent trajectories.

The paper identifies 3D regulatory hubs involved in sex determination using spatial auto-correlation analysis in mouse embryos.

This study compares two methods for isolating cardiac progenitor cells, finding that the collagenase-trypsin protocol yields more cells and shares a gene expression profile with cardiosphere-derived cells.

The paper identifies a phospho-switch in SALL4 that controls cell fate by modulating BAF complex interaction in response to BMP4-DUSP9 signaling, causing developmental defects when disrupted.

The paper identifies Wnt signaling as essential for coronary artery endothelial cell reprogramming and collateral artery formation in mice, with implications for cardiovascular disease.

This study compares the biological and biomechanical features of mandibular condylar cartilage and articular cartilage in mice, revealing distinct structural and functional differences.

This paper develops PCR-based techniques for early in ovo sexing and genotyping of chicken embryos, improving efficiency and ethical standards in animal research.

This study reconstructs 3D spatial transcriptomic models of planarians to map cell type distribution and positional gene regulation, identifying candidate genes involved in regeneration.

This study examines age- and light-dependent changes in the ultrastructure of the zebrafish olfactory epithelium using light and transmission electron microscopy.