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The YjfJ protein is the effector of a second PspA/VIPP1 system that is widespread in the Gammaproteobacteria

The paper identifies a second PspA/VIPP1 system in Gammaproteobacteria, characterized by YjfJ-like proteins, which are prevalent and functionally distinct from the canonical PspA system.

Mitochondria-Coupled Hitchhiking Drives Vimentin Intermediate Filament Transport

The paper shows that vimentin intermediate filaments (VIFs) hitchhike on motile mitochondria for transport, rather than directly engaging microtubules.

High-density environmental DNA metabarcoding reveals fine-scale three-dimensional structure of a fish community in a semi-closed bay

The paper uses high-density eDNA metabarcoding to reveal three-dimensional fish community structure in a semi-closed bay, showing significant horizontal and vertical variation not fully explained by environmental variables.

Sarrella massiliensis gen. nov. sp. nov., a new gut genus isolated from the stool of a healthy donor

The paper isolates and describes a new gut bacterial genus, Sarrella massiliensis, from a healthy donor's stool using culturomics.

CD90 identifies distinct fractions of muscle stem cells with different modalities of activation and quiescence maintenance

The paper identifies CD90 as a marker distinguishing two muscle stem cell subpopulations with different activation kinetics and quiescence maintenance mechanisms in mice and humans.

GOParsimony: parsimonious saltation across the Gene Ontology digraph for efficient functional annotation

GOParsimony filters GO terms to identify the most parsimonious functional annotations for gene/protein sets, outperforming existing methods in yeast and human data.

Social copying drives spatial allocation in gregarious herbivores

The paper investigates resting patch selection in cattle using GPS data and a model showing social copying drives spatial allocation.

A large, distinct family of RNase H fold nucleases associated with numerous defense systems in prokaryotes

The paper identifies and characterizes a new family of prokaryotic defense proteins, WARDs, which are associated with various defense systems and provide phage resistance.

Presynaptic PMCA interacts with Dlg, regulating in vivo synaptic calcium in Drosophila larval NMJ

This study shows that PMCA interacts with Dlg to regulate presynaptic calcium levels in Drosophila NMJ, affecting neurotransmitter release and Ca2+ homeostasis.

De novo genome assembly of the floating-hook moss Warnstorfia fluitans

This paper presents the first de novo genome assembly of the floating-hook moss Warnstorfia fluitans, along with its chloroplast and mitochondrial genomes, providing a resource for ecological and evolutionary studies.

Sourmash accurately profiles strains from long-read metagenomes preserving gene content

This study evaluates Sourmash's ability to profile microbial strains from long-read metagenomes, showing accurate gene content recovery and abundance estimation.

Intra-individual changes to peak alpha frequency map to pain perception following high frequency sensitisation of central nociceptive pathways: A test-retest reliability study

This study examines intra-individual changes in peak alpha frequency and -band power in EEG data following high-frequency sensitisation of central nociceptive pathways, assessing test-retest reliability and their relation to pain perception.

Neural dynamics become significantly faster and more nonlinear at the peak of information processing

The paper shows that neural populations adjust their optimal temporal resolution during stimulus processing, becoming faster and more nonlinear when decoding information is most accurate.

The chromatin-associated PWO proteins interface with circadian and epigenetic signaling to regulate flowering time in Arabidopsis

This study investigates how PWO1 and PWO2 proteins interact with circadian and epigenetic signaling to regulate flowering time in Arabidopsis.

Life on leaves left a lasting mark on the Methylobacterium core genome

The study examines the core genome evolution of Methylobacterium to show that genes related to phyllosphere adaptation show greater evolutionary discordance, suggesting horizontal gene transfer.

A fibroblast-CD8+ T cell circuit drives a Type 1 shift in allergic inflammatory memory

This study identifies a fibroblast-CD8+ T cell circuit that drives a Type 1 immune shift in allergic inflammatory memory through mechanistic and translational analysis in murine and human models.

High-fat diet promotes exhaustion-associated T-cell remodeling across vascular and lymphoid tissues in atherosclerosis-prone mice

This study shows that a high-fat diet causes T-cell exhaustion in multiple tissues of atherosclerosis-prone mice, which partially reverses with dietary changes.

Where single-cell foundation models help: a benchmark of annotation, perturbation and regulatory inference against simple baselines

This paper benchmarks single-cell foundation models against baselines for annotation, perturbation and regulatory inference using diverse datasets.

FGF signaling induces disease-associated oligodendrocyte states and drives myelin pathology

This study shows FGF signaling induces disease-associated oligodendrocyte states and causes myelin pathology in both in vitro and in vivo models.

Disrupted mannosidase enzymes in C9orf72 ALS/FTD

The paper identifies reduced Golgi enzymes MAN1A1 and MAN1A2 in ALS-associated microglia and astrocytes, linking impaired glycan metabolism to neuroinflammation and disease mechanisms.