A. Erickson

Immunosuppression in the prostate tumor microenvironment is tied to androgen deprivation therapy-resistant club-like cells

The paper identifies club-like cells in the prostate tumor microenvironment that contribute to androgen deprivation therapy resistance through immune suppression.

IRF7 impacts on prostate cancer cell survival in response to radiation

This study investigates how IRF7 influences prostate cancer cell survival after radiation and identifies therapeutic vulnerabilities linked to IRF7 expression.

PME-1 suppresses anoikis, and is associated with therapy relapse of PTEN-deficient prostate cancers

This study identifies PME-1 as a biomarker for aggressive PTEN-deficient prostate cancers by showing its role in suppressing anoikis.

Proteomics profiling reveals regulation of immune response to Salmonella Typhimurium infection in mice

The paper uses proteomics to compare immune responses to Salmonella Typhimurium infection in two mouse strains, identifying differentially expressed proteins and pathways involved in resistance.

Liver Organoid and T Cell Coculture Models Cytotoxic T Cell Responses against Hepatitis C Virus

This paper develops a microfluidic coculture system of liver organoids and T cells to study HCV-specific cytotoxic T cell responses in vitro.

Single-cell ATAC and RNA sequencing reveal pre-existing and persistent subpopulations of cells associated with relapse of prostate cancer

The paper uses single-cell ATAC and RNA sequencing to identify pre-existing and treatment-persistent stem-like cell subpopulations in prostate cancer models that predict treatment response.

Time resolved quantitative phosphoproteomics reveals distinct patterns of SHP2 dependence in EGFR signaling

The paper uses time-resolved phosphoproteomics to analyze SHP2's role in EGFR signaling, identifying distinct phosphotyrosine response patterns upon SHP099 treatment.

A forest model intercomparison framework and application at two temperate forests along the East Coast of the United States

This paper develops a framework for comparing forest models and applies it to two models at two temperate forest sites, finding PPA-SiBGC outperformed LANDIS-II NECN across multiple metrics.

Implementation of the Perfect Plasticity Approximation with biogeochemical compartments in R

The paper presents a forest biogeochemistry model implemented in R, using the Perfect Plasticity Approximation and empirical vegetation dynamics to estimate carbon and nitrogen fluxes.