Author

A. M. Vaghasia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1 Organism:mouse· 1

Frequent Co-Authors

S. Yegnasubramanian· 3 shared A. M. De Marzo· 2 shared J. Liu· 2 shared M. C. Haffner· 2 shared N. Castagna· 2 shared R. Chikarmane· 2 shared W. G. Nelson· 2 shared A. Bhamidipati· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersCell Biology

S. Yegnasubramanian

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Author profile →

3 papers

Recent·Most cited

RepairSwitch: simultaneous functional assessment of homologous recombination and end joining DNA repair pathways in living cells

R. C. Steinberg, J. Liu, A. M. Vaghasia, H. Giovinazzo, M.-T. N. Pham, D. Tselenchuk, R. Chikarmane, M. C. Haffner, W. G. Nelson, S. Yegnasubramanian

The paper introduces RepairSwitch, a flow cytometry assay to simultaneously measure HR and NHEJ DNA repair rates in living cells, and demonstrates its utility in assessing drug and genetic perturbations.

bioRxiv · Jan 17, 2023 · PreprintCell Biology

Single-cell atlas of epithelial and stromal cell heterogeneity by lobe and strain in the mouse prostate

M. K. Graham, R. Chikarmane, R. Wang, A. M. Vaghasia, A. Gupta, Q. Zheng, B. P. Wodu, X. Pan, N. Castagna, J. Liu, J. Meyers, A. Skaist, S. J. Wheelan, B. W. Simons, C. Bieberich, , S. Yegnasubramanian

The paper constructs a single-cell atlas of mouse prostate cell types across strains and lobes, revealing strain- and lobe-specific transcriptomic differences in epithelial cells and strain-lobespecific fibroblast subtypes.

bioRxiv · Jan 31, 2022Cell Biology

PHENOTYPIC CHARACTERIZATION OF TWO NOVEL CELL LINE MODELS OF CASTRATION RESISTANT PROSTATE CANCER.

M. C. Haffner, A. Bhamidipati, H. K. Tsai, D. M. Esopi, A. M. Vaghasia, J.-Y. Low, R. A. Patel, G. Guner, M.-T. Pham, N. Castagna, J. Hicks, N. Wyhs, R. Aebersold, A. M. De Marzo, W. G. Nelson, , S. Yegnasubramanian

This study develops two novel castration-resistant prostate cancer cell lines and characterizes their transcriptomic and proteomic profiles to understand resistance mechanisms.

bioRxiv · Jul 4, 2021 · PreprintCancer Biology