Author

Brandon Sullivan

Ragon Institute of MGH, MIT and Harvard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Hernandez Moura SilvaiD· 2 shared Arundeep SinghiD· 1 shared Beatriz BurgeriD· 1 shared C. Henrique SerezaniiD· 1 shared Charles Evavold· 1 shared Dig Bijay MahatiD· 1 shared Emily MetcalfiD· 1 shared Enrico MoisoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

Hernandez Moura SilvaORCID

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2 papers

Recent·Most cited

Oleic acid suppresses NLRP3 inflammasome activation to prevent dermal macrophage death and limit imiquimod-induced psoriasis

Beatriz Burger, Roberta Nicolli Sagiorato, Isabela Buquio Baccarin, Vítor Rosetto Muñoz, Gabriella Cerna, Ilya Andreev, Nathalia Araujo, Hui Sophie Shu, Jia Zhao, Brandon Sullivan, Yisha Liang, Rodrigo Angelo Martinati Bistaffa, Vitoria Christina Gaspar, Esther Midori Yabuuti, Natalie Bittencourt Ramos, , Hosana Gomes Rodrigues

This study shows that oleic acid reduces NLRP3 inflammasome activity in macrophages, preventing their death and limiting psoriasis-like skin inflammation in mice.

bioRxiv · Nov 1, 2026 · PreprintImmunology

Mutant p53 Exploits Enhancers to Elevate Immunosuppressive Chemokine Expression and Impair Immune Checkpoint Inhibitors in Pancreatic Cancer

Dig Bijay Mahat, Heena Kumra, Sarah A Castro, Emily Metcalf, Kim Bich Nguyen, Ryo Morisue, William W. Ho, Ivy X. Chen, Brandon Sullivan, L. K. Yim, Arundeep Singh, Jiayu Fu, Sean K. Waterton, Yu‐Chi Cheng, Sylvie Roberge, , Phillip A. Sharp

This study shows mutant p53R172H in pancreatic cancer enhances immunosuppressive chemokine Cxcl1 expression via enhancer activation, reducing immune checkpoint inhibitor efficacy.

Immunity · Jul 1, 2025Peer-reviewedCancer Biology