Author

C. L. Vinhaes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:rat· 2 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

B. B. Andrade· 3 shared A. Sette· 2 shared C. E. Nelson· 2 shared D. L. Barber· 2 shared D. Oliveira-de-Souza· 2 shared J. Kabat· 2 shared K. D. Kauffman· 2 shared L. E. Via· 2 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

B. B. Andrade

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Author profile →

3 papers

Recent·Most cited

CD4 T cells are rapidly depleted from tuberculosis granulomas following acute SIV co-infection

T. W. Foreman, C. E. Nelson, K. D. Kauffman, N. E. Lora, C. L. Vinhaes, D. E. Dorosky, S. W. Sakai, F. Gomez, J. D. Fleegle, M. Parham, S. R. Perera, C. S. Lindestam Arlehamn, A. Sette, Tuberculosis Imaging Program, J. M. Brenchley, , D. L. Barber

This study shows that acute SIV co-infection rapidly depletes CD4 T cells from tuberculosis granulomas before systemic CD4 T cell loss or disease reactivation.

bioRxiv · Dec 17, 2021Immunology

PD-1 blockade exacerbates Mycobacterium tuberculosis infection in rhesus macaques

K. D. Kauffman, S. Sakai, N. E. Lora, S. Namasivayam, P. J. Baker, O. Kamenyeva, T. W. Foreman, C. E. Nelson, D. Oliveira-de-Souza, C. L. Vinhaes, Z. Yaniv, C. S. Lindestam Arleham, A. Sette, G. J. Freeman, R. Moore, , D. L. Barber

This study shows that PD-1 blockade worsens Mycobacterium tuberculosis infection in rhesus macaques by increasing bacterial loads and altering immune responses.

bioRxiv · Aug 5, 2020Immunology

Aging increases the systemic molecular degree of inflammatory perturbation in patients with tuberculosis

D. Oliveira-de-Souza, C. L. Vinhaes, M. B. Arriaga, N. Pavan Kumar, A. T. L. Queiroz, K. F. Fukutani, S. Babu, B. B. Andrade

This study finds that aging increases the molecular degree of inflammatory perturbation in tuberculosis patients, with higher values observed in adults compared to children.

bioRxiv · Mar 10, 2020Immunology