The neuroimmune CGRP-RAMP1 axis tunes cutaneous adaptive immunity to the microbiota
W. Kulalert, A. C. Wells, V. M. Link, A. I. Lim, N. Bouladoux, M. Nagai, O. J. Harrison, O. Kamenyeva, J. Kabat, M. Enamorado, I. Chiu, Y. Belkaid
This study identifies a neuroimmune CGRP-RAMP1 axis that modulates cutaneous adaptive immunity to the microbiota by constraining Type 17 responses and limiting T cell activation.
bioRxiv · Dec 26, 2023 · PreprintImmunology