Author

G. J. Freeman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:CITE-seq· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Sher· 2 shared D. L. Barber· 2 shared K. D. Kauffman· 2 shared L. E. Via· 2 shared N. E. Lora· 2 shared S. Namasivayam· 2 shared S. Sakai· 2 shared A. E. Baxter· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

A. Sher

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Losartan controls immune checkpoint blocker-induced edema and improves survival in glioblastoma

M. Datta, S. Chatterjee, E. M. Perez, S. Gritsch, S. Roberge, M. Duquette, I. X. Chen, K. Naxerova, A. S. Kumar, M. Ghosh, K. E. Emblem, M. R. Ng, W. W. Ho, P. Kumar, S. Krishnan, , R. K. Jain

Losartan prevents ICB-induced cerebral edema and improves survival in glioblastoma mice, with a predictive immune signature identified.

bioRxiv · Jun 28, 2022 · PreprintCancer Biology

Immune checkpoint expression on HIV-specific CD4+ T cells and response to their blockade are dependent on lineage and function

E. Brunet-Ratnasingham, A. Morou, M. Dube, J. Niessl, A. E. Baxter, O. Tastet, N. Brassard, G. Ortega-Delgado, R. Charlebois, G. J. Freeman, C. Tremblay, J.-P. Routy, D. E. Kaufmann

bioRxiv · Sep 23, 2021Immunology

Functional inactivation of pulmonary MAIT cells following 5-OP-RU treatment of non-human primates

S. Sakai, N. E. Lora, K. D. Kauffman, D. E. Dorosky, S. Oh, S. Namasivayam, F. Gomez, J. D. Fleegle, C. S. Lindestam Arlehamn, A. Sher, G. J. Freeman, L. E. Via, C. E. Barry, D. L. Barber

This study shows that 5-OP-RU treatment of M. tuberculosis-infected rhesus macaques leads to MAIT cell dysfunction rather than expansion, with upregulated PD-1 and loss of cytokine production.

bioRxiv · Jan 29, 2021Immunology

PD-1 blockade exacerbates Mycobacterium tuberculosis infection in rhesus macaques

K. D. Kauffman, S. Sakai, N. E. Lora, S. Namasivayam, P. J. Baker, O. Kamenyeva, T. W. Foreman, C. E. Nelson, D. Oliveira-de-Souza, C. L. Vinhaes, Z. Yaniv, C. S. Lindestam Arleham, A. Sette, G. J. Freeman, R. Moore, , D. L. Barber

This study shows that PD-1 blockade worsens Mycobacterium tuberculosis infection in rhesus macaques by increasing bacterial loads and altering immune responses.

bioRxiv · Aug 5, 2020Immunology