C. Liu

The paper develops a mass-flow immigration model to quantify influent microorganism immigration efficiency and their contribution to organic substrate consumption in activated sludge.

This study reveals the pathway and mechanism of TRiC-mediated tubulin folding using cryo-EM structures and XL-MS, showing how tubulin is stabilized during the ATPase cycle.

This study uses functional ultrasound imaging to evaluate spinal cord hemodynamics in humans during epidural stimulation, revealing new insights into spinal circuitry and blood flow responses.

This study uses native mass spectrometry and structural analysis to show how copper and lipids regulate the ABC transporter MsbA, revealing a conserved KLA binding site that modulates ATPase activity.

This study identifies TMEM65's role in mitochondrial calcium regulation, showing its loss causes mitochondrial disease and suggesting therapeutic targeting of mitochondrial calcium as a potential treatment.

This study compares Babesia and Plasmodium genomes and gene expression to explain why Babesia is not killed by artemisinin, finding differences in haem synthesis, iron utilization, and gene expression.

This paper develops multispecific antibodies that neutralize all SARS-CoV-2 variants, including Omicron, by targeting multiple epitopes on the spike protein.

The paper shows that obesity increases DNA damage in breast epithelium of BRCA mutation carriers and suggests targeting estrogen or metabolic dysfunction may reduce breast cancer risk.

This study examines how post-stroke individuals' reactive balance control strategies during walking are impaired, showing reduced ability to modulate ground reaction forces to recover from forward balance loss.

The paper introduces deep-APQ, a proteome quantitation method using segmented MS/MS acquisition of a1 ions, showing improved coverage and accuracy in E. coli proteome analysis.

This study examines age-related seroprevalence of four seasonal coronaviruses in children and postpartum women, showing waning passive immunity and resurgence of IgGs with age.

This study uses cryo-EM to reveal structural details of TRiC/CCT-mediated folding of tubulin and actin with plp2, showing how plp2 coordinates substrate translocation and folding.

This study identifies a novel subtype of HRD in HBVHCC caused by CDW19S perturbation and shows it can be targeted therapeutically.

This study identifies socio-ecological predictors that explain country-level alien species richness and capacity to manage biological invasions, revealing historical influences of governance and trade.

The paper identifies IRs near genes in Arabidopsis thaliana that influence chromatin topology and gene expression, with phenotypic consequences.

This study identifies Hsp25/27 as a key mediator of mucosal healing by integrating host and microbial signals in intestinal epithelial cells following inflammatory injury.

This study shows GT0918 reduces cytokine release and inflammation in COVID-19 by inhibiting NF-κB and activating NRF2, suggesting its potential for treating both mild and severe cases.

This paper introduces a self-blinking DNA probe for 3D superresolution imaging of native chromatin in live cells, revealing chromatin organization and decompaction dynamics.

This study compares immune responses between individuals with sterilizing protection against TB and those with latent infection to identify potential vaccine targets.

This paper shows that ascorbic acid-derived carbon dots (VCDs) improve circadian rhythm and reduce hyperactive behavior in a zebrafish ADHD model caused by per1b mutation.

This paper identifies three substitutions in SARS-CoV-2 3CLpro that confer resistance to nirmatrelvir and other 3CLpro inhibitors in vitro.

The paper identifies a membrane-condensate interface in Arabidopsis processing bodies that controls cell shape through actin dynamics.

This study shows that BA.4 and BA.5 variants are more resistant to neutralization by vaccine and BA.1 immune sera compared to BA.1 and BA.2.

This study shows Hsp27 binds phosphorylated Tau to prevent its aggregation and mitigate AD pathology.

This study develops Stereo-seq, a high-resolution spatial transcriptomic method, to analyze mouse organogenesis and map developmental disease loci.

The paper presents a single-cell transcriptomic atlas of Macaca fascicularis, identifying cell interactions and disease associations.

The paper shows that phase separation of SEC14-like protein, mediated by proteolysis, maintains auxin efflux carrier polarity at Arabidopsis plasma membranes, contributing to root developmental robustness.

The paper introduces a microfluidic chip for co-culture studies that enables controlled paracrine signaling and high throughput.

The paper shows that CMT3 and KRYPTONITE maintain the sulfurea paramutation in tomato by affecting CHG hypermethylation and chromatin structure, but not the PolV-dependent RdDM pathway.