Author

C. Scanga

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:non-human primate· 5 Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Research Focus:cell type annotation· 2 Assay:imaging· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Assay:clinical cohort / trial· 1

Frequent Co-Authors

P. Maiello· 4 shared C. Ameel· 3 shared J. L. Flynn· 3 shared M. Rodgers· 3 shared A. G. White· 2 shared A. K. Shalek· 2 shared E. Klein· 2 shared H. J. Borish· 2 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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4 shared papersImmunology

P. Maiello

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

CD4+ T cells are homeostatic regulators during Mtb reinfection

J. Bromley, S. K. C. Ganchua, S. K. Nyquist, P. Maiello, M. Chao, H. J. Borish, M. Rodgers, J. Tomko, K. Kracinovsky, D. Mugahid, S. N. Nguyen, D. Wang, J. M. Rosenberg, E. C. Klein, H. P. Gideon, , J. L. Flynn

The paper shows that CD4+ T cells reduce inflammation and disease severity during Mtb reinfection by reprogramming CD8+ T cells and innate immune cells.

bioRxiv · Dec 20, 2023 · PreprintImmunology

Multimodal profiling of lung granulomas reveals cellular correlates of tuberculosis control

H. P. Gideon, T. K. Hughes, C. N. Tzouanas, M. H. Wadsworth, A. A. Tu, T. M. Gierahn, J. M. Peters, F. H. Hopkins, J.-R. Wei, C. Kummerlowe, N. L. Grant, K. Nargan, J. Phuah, H. J. Borish, P. Maiello, , A. K. Shalek

The paper identifies cellular and temporal factors associated with bacterial control in tuberculosis granulomas using multimodal data.

bioRxiv · Oct 24, 2020 · PreprintImmunology

SARS-CoV-2 infection of African green monkeys results in mild respiratory disease discernible by PET/CT imaging and prolonged shedding of infectious virus from both respiratory and gastrointestinal tracts

A. L. Hartman, S. Nambulli, C. M. McMillen, A. G. White, N. Tilston-Lunel, J. R. Albe, E. L. Cottle, M. D. Dunn, L. J. Frye, T. H. Gilliland, E. L. Olsen, K. J. O'Malley, M. M. Schwarz, J. A. Tomko, R. C. Walker, , W. P. Duprex

bioRxiv · Jun 20, 2020Microbiology

MAIT cells are minimally responsive to Mycobacterium tuberculosis within granulomas, but are functionally impaired by SIV in a macaque model of SIV and Mtb co-infection

A. L. Ellis, A. J. Balgeman, E. C. Larson, M. Rodgers, C. Ameel, T. Baranowski, P. Maiello, J. Juno, C. Scanga, S. L. O'Connor

This study examines MAIT cell function in a macaque model of SIV and Mtb co-infection, finding minimal Mtb responsiveness within granulomas and impaired TNF secretion during co-infection.

bioRxiv · Jan 7, 2020 · PreprintImmunology

Pre-existing SIV Infection Increases Susceptibility to Tuberculosis in Mauritian Cynomolgus Macaques

M. Rodgers, C. Ameel, A. Ellis-Connell, A. Balgeman, P. Maiello, G. Barry, T. Friedrich, E. Klein, S. O'Connor, C. Scanga

This study shows that pre-existing SIV infection in macaques increases susceptibility to tuberculosis by impairing immune control of M.tb.

bioRxiv · Jul 3, 2018Immunology