C. Song

This paper shows nasal delivery of a camelid single-domain antibody reduces SARS-CoV-2 titers in hamsters without weight loss or cytokine induction.

This study identifies DDX21 cleavage by caspase-3/6 during virus infection as a mechanism to suppress IFN-β signaling by disrupting the DDX1-DDX21-DHX36 complex.

This study investigates how the absence of the SP-R210L isoform in macrophages leads to a hyper-inflammatory state through altered genomic and epigenomic responses.

This paper develops a theoretical framework to classify priority effects in multispecies communities and demonstrates its utility using neural networks and experimental data.

The paper reports high-resolution structures of PSI-LHCI-LHCII supercomplex in green algae, revealing the role of LhcbM5 in state transitions and supercomplex formation.

This study shows that IBV uses nsp15 to inhibit stress granule formation, thereby evading antiviral responses and promoting viral replication.

The paper investigates the structure of tokyovirus, a Marseilleviridae giant virus, revealing a novel capsid protein network that forms its characteristic inner membrane structure.

The paper introduces membrane contact probability (MCP) as a predictive metric for membrane proteins, showing it improves contact map and structure predictions.

This study shows CD117/c-kit expression in prostate cancer cells correlates with poor survival and promotes aggressiveness, migration, and TKI resistance through CSC-like properties.

This study shows that Newcastle disease virus induces ferroptosis in tumor cells via the p53-SLC7A11-GPX4 pathway, leading to nutrient deprivation and cell death.

The paper develops a novel isothermal amplification method (LMCP) for detecting Oryza sativa ITS with higher sensitivity and speed compared to LAMP.

This study isolates and identifies phosphate-solubilizing bacteria from soybean rhizosphere soil, finding strains that promote plant growth through organic acid secretion and indole acetic acid production.

This study investigates the association between IFNL4 genetic variants and HCV-related cirrhosis and HCC risk, finding protective effects against cirrhosis and increased HCC risk in specific populations.

The paper demonstrates that NC410, a LAIR-2 Fc protein, blocks LAIR-1-collagen interaction, enhancing T cell activity and reducing tumor growth in humanized models.

The paper introduces a hypergraph-based formalism to analyze coexistence in multispecies systems, revealing predictable discontinuities called coexistence holes.

The paper develops a theoretical framework to explain deterministic and contingent competitive exclusion in multispecies communities using an empirical plant competition system.

This study examines amyloid β fibril formation under microgravity conditions on the ISS, finding slower progression and distinct morphologies compared to ground-based experiments.

This study evaluates the cytotoxicity of chloroquine and hydroxychloroquine in multiple cell lines and tissues using a dynamic imaging system and PBPK model, finding HCQ less toxic than CQ in most cases.

This study examines ACE2 receptor usage by SARS-CoV-2 across 14 mammalian species, finding broad receptor activity and implications for zoonotic transmission and animal models.

This paper bridges parametric and nonparametric measures of species interactions to reveal new insights into non-equilibrium ecological dynamics.

This study shows that using computational modeling to teach metabolism improves student performance and may enhance educational equity.

This study shows that the protruding domain of norovirus capsids dynamically rotates between rising and resting conformations in response to pH and metal ions, enhancing infection efficiency.

This study measures 3-D morphology changes in human red blood cells under localized photothermal effects using gold nanorods and 3D quantitative phase imaging.

This paper reveals the atomistic mechanism of NompC channel opening under intracellular compression using simulations and experiments, showing force transmission through ankyrin repeats and linker helices to the TRP domain.

This study determines the cryo-EM structure of RyR1 and uses simulations to analyze cation hydration and conduction mechanisms in the receptor.

The paper isolates an Asgard archaeon and proposes a symbiosis model for eukaryogenesis based on its morphology and metabolism.

This study reveals the Ca2+ permeation mechanism through RyR1 using molecular dynamics simulations, showing a one-at-a-time hydrated ion translocation pattern.

The paper reports a quadruple mutant of hepatitis B virus showing moderate resistance to tenofovir and demonstrates that combination therapy with entecavir and tenofovir effectively suppresses this resistant mutant.

This study identifies TMC1 as providing a background leak conductance in mouse auditory hair cells, essential for action potential firing and tonotopic organization.

This study identifies CHOP and IRE1α-XBP1/JNK signaling as mediators of NDV-induced apoptosis and their role in promoting virus proliferation in tumor cells.