Author

Katharina Boroviak

Wellcome Sanger Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Microbiology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Organism:plant (other)· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Abdel AyadiiD· 1 shared Adam CaulderiD· 1 shared Alasdair J. AllaniD· 1 shared Alasdair J. GibbiD· 1 shared Alex Fower· 1 shared Allan BradleyiD· 1 shared Amie Creighton· 1 shared Angelina Gaspero· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenetics

Abdel AyadiORCID

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Author profile →

3 papers

Recent·Most cited

Impact of Essential Genes on the Success of Genome Editing Experiments Generating 3,313 New Genetically Engineered Mouse Lines

Hillary Elrick, Kevin A. Peterson, Brandon Willis, Denise Grant Lanza, Elif Fidan Acar, Edward J. Ryder, Lydia Teboul, Petr Kašpárek, Marie‐Christine Birling, David J. Adams, Allan Bradley, Robert E. Braun, Steve D. M. Brown, Adam Caulder, Gemma F. Codner, , Valerie Laurin

The paper analyzes 3,313 genetically engineered mouse lines to identify gene essentiality as the main factor affecting Cas9-based genome editing success.

Scientific Reports · Sep 30, 2024Peer-reviewedGenetics

A novel chemogenomic screening platform for scalable antimalarial drug target identification

Christopher Bower-Lepts, Mukul Rawat, William Collins Keith, Gareth Girling, Madeline R. Luth, Krypton Carolino, Katharina Boroviak, Rachael Coyle, Frank Schwach, Cindy Smidt, Ellen Bushell, Sonia Moliner Cubel, Maria De Gracia Gomez-Lorenzo, Francisco‐Javier Gamo, Elizabeth A. Winzeler, , Julian C. Rayner

This paper develops a chemogenomic platform using Plasmodium berghei artificial chromosomes to identify antimalarial drug targets through barcode sequencing and validation in Plasmodium falciparum.

bioRxiv · Aug 27, 2024 · PreprintMicrobiology

A genetic variant of the Wnt receptor LRP6 accelerates synapse degeneration during ageing and in Alzheimer's disease

Megan E. Jones, Johanna Buechler, Tom Dufor, Katharina Boroviak, Emmanouil Metzakopian, Alasdair J. Gibb, Patricia C. Salinas

bioRxiv · Apr 6, 2022 · PreprintNeuroscience