Author

E. Y. Jones

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 2 Research Focus:protein structure prediction· 2 Assay:structural biology· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:deconvolution· 1

Frequent Co-Authors

K. Harlos· 3 shared F.-L. Hsieh· 2 shared T.-H. Chang· 2 shared A. C. Kalli· 1 shared A. Chu· 1 shared A. J. McMichael· 1 shared A. L. Duncan· 1 shared A. Townsend· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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3 shared papersBiochemistry

K. Harlos

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Structural basis of Norrin recognition by Lgr4/5/6

T.-H. Chang, K. Harlos, F.-L. Hsieh, E. Y. Jones

The paper determines the structure of Norrin bound to Lgr4ECD, showing conserved binding residues and overlapping binding sites with Rspo1 and Fz4CRD.

bioRxiv · Sep 29, 2022 · PreprintBiochemistry

Structural insights into Frizzled assembly by acylated Wnt and Frizzled Connector domain

T.-H. Chang, F.-L. Hsieh, K. Harlos, E. Y. Jones

The paper reports structures of Frizzled domains complexed with acylated Wnt peptide, revealing different dimer conformations and interactions that inform Fz function modulation.

bioRxiv · Sep 29, 2022 · PreprintBiochemistry

Mouse and Human Antibodies that Bind HLA-E-Leader Peptide Complexes and Enhance NK Cell Cytotoxicity

D. Li, S. Brackenridge, L. C. Walters, O. Swanson, K. Harlos, D. Rozbesky, D. W. Cain, K. Wiehe, R. M. Scearce, M. Barr, Z. Mu, R. Parks, M. Quastel, R. J. Edwards, Y. Wang, , B. F. Haynes

The paper isolates antibodies that bind HLA-E-Leader peptide complexes and enhance NK cell cytotoxicity in both mice and humans.

bioRxiv · Dec 3, 2020Immunology

The guidance and adhesion protein FLRT2 dimerizes in cis via dual Small-X3-Small transmembrane motifs

V. Jackson, J. Hermann, C. J. Tynan, D. J. Rolfe, R. A. Corey, A. L. Duncan, M. Noriega, A. Chu, A. C. Kalli, E. Y. Jones, M. Sansom, M. L. Martin-Fernandez, E. Seiradake, M. Chavent

This study identifies cis dimerization of FLRT2 via transmembrane and extracellular motifs, suggesting a competitive interaction mechanism with trans interactions.

bioRxiv · Oct 6, 2020Biophysics

Semaphorin 3A induces cytoskeletal paralysis in tumor-specific CD8+ T cells

M. B. Barnkob, Y. S. Michaels, V. Andre, P. S. Macklin, U. Gileadi, S. Valvo, M. Rei, C. Kulicke, J.-L. Chen, V. Jain, V. Woodcock, H. Colin-York, A. V. Hadjinicolaou, Y. Kong, V. Mayya, , V. Cerundolo

This study shows Sema3A inhibits tumor-specific CD8+ T cell function by inducing cytoskeletal paralysis via NRP1 in the tumor microenvironment.

bioRxiv · Nov 20, 2019Immunology

Robin Hood: non-fitting, non-smoothing image detrending for bleaching correction

R. Nolan, M. Iliopoulou, C. Siebold, E. Y. Jones, S. Padilla-Parra

The paper introduces Robin Hood, an automatic detrending algorithm for fluorescence microscopy that performs well at low intensities, and evaluates it using simulated and low photon budget live cell images.

bioRxiv · Jun 14, 2019 · PreprintBiophysics