Author

Elizabeth L. Calder

Memorial Sloan Kettering Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:metabolomics· 2 Approach:statistical model· 2 Assay:electronic health records· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Lorenz StuderiD· 4 shared Benjamin I. Schwartz· 2 shared Csaba KonràdiD· 2 shared Davinder K. Sandhu· 2 shared Dipa Roychoudhury· 2 shared Giovanni ManfrediiD· 2 shared Hibiki KawamataiD· 2 shared Kirsten G. BredvikiD· 2 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersNeuroscience

Lorenz StuderORCID

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Author profile →

4 papers

Recent·Most cited

Combined small molecule treatment accelerates timing of maturation in human pluripotent stem cell-derived neurons

Emiliano Hergenreder, Andrew P. Minotti, Yana Zorina, Polina Oberst, Zeping Zhao, Hermany Munguba, Elizabeth L. Calder, Arianna Baggiolini, Ryan M. Walsh, Conor M. Liston, Joshua Levitz, Ralph J. Garippa, Shuibing Chen, Gabriele Ciceri, Lorenz Studer

This study identifies a drug cocktail that accelerates maturation of hPSC-derived neurons and other cell types through pharmacological intervention.

Nature Biotechnology · Jan 2, 2024Peer-reviewedNeuroscience

Deriving Schwann Cells from hPSCs Enables Disease Modeling and Drug Discovery for Diabetic Peripheral Neuropathy

Homa Majd, Sadaf Amin, Zaniar Ghazizadeh, Andrius Cesiulis, Edgardo J. Arroyo, Karen L. Lankford, Alireza Majd, Sina Farahvashi, Angeline K Chemel, Mesomachukwu Okoye, Megan D. Scantlen, Jason H. Tchieu, Elizabeth L. Calder, Valerie Le Rouzic, Bradley Shibata, , Faranak Fattahi

This study derives Schwann cells from human pluripotent stem cells to model diabetic peripheral neuropathy and identify a drug candidate that rescues sensory function and prevents myelin damage.

Cell stem cell · May 1, 2023Peer-reviewedDevelopmental Biology

Accelerated trans-sulfuration metabolically defines a discrete subclass of ALS patients

Qiuying Chen, Davinder K. Sandhu, Csaba Konràd, Dipa Roychoudhury, Benjamin I. Schwartz, Roger R. Cheng, Kirsten G. Bredvik, Hibiki Kawamata, Elizabeth L. Calder, Lorenz Studer, Steven M. Fischer, Giovanni Manfredi, Steven S. Gross

The paper identifies a subclass of sporadic ALS patients with metabolic defects in trans-sulfuration, characterized by increased cysteine and glutathione synthesis and distinct metabolic responses.

bioRxiv · Apr 16, 2019 · PreprintNeuroscience

Identification of a Distinct Metabolomic Subtype of Sporadic ALS Patients

Qiuying Chen, Davinder K. Sandhu, Csaba Konràd, Dipa Roychoudhury, Benjamin I. Schwartz, Roger R. Cheng, Kirsten G. Bredvik, Hibiki Kawamata, Elizabeth L. Calder, Lorenz Studer, Steven M. Fischer, Giovanni Manfredi, Steven S. Gross

The paper identifies a distinct metabolomic subtype in sporadic ALS patients through metabolite profiling and multi-omics integration, showing increased cysteine metabolism and potential therapeutic targets.

bioRxiv · Sep 13, 2018 · PreprintNeuroscience