M. Rettel

A multi-year longitudinal harmonization of quality controls in mass spectrometry proteomics core facilities

This study harmonizes quality controls across proteomics core facilities to improve data comparability and reliability through a 4-year longitudinal dataset and common processing software.

Revealing the Arabidopsis AtGRP7 mRNA binding proteome by specific enhanced RNA interactome capture

The paper identifies proteins interacting with the AtGRP7 mRNA in Arabidopsis using enhanced RNA interactome capture, revealing ALBA proteins as binders.

Structural Insights into The Role of MAGEA4 in RAD18 Regulation: Implications for Ubiquitin Ligase-Binding across the MAGE Protein Family

This study identifies the interaction between MAGEA4 and RAD18 using NMR and AlphaFold2, revealing structural insights into how MAGEA4 regulates RAD18's ubiquitination activity and its implications for cancer.

Structure of the mycobacterial ESX-5 Type VII Secretion System hexameric pore complex

The paper presents a high-resolution cryo-EM structure of the ESX-5 Type VII secretion system hexameric pore complex, revealing its assembly and potential gating mechanisms.

Pharmacological inhibition of nonsense-mediated RNA decay augments HLA class I-mediated presentation of neoepitopes in MSI CRC

The paper shows that inhibiting nonsense-mediated RNA decay increases HLA class I presentation of neoepitopes from frameshift mutations in MSI colorectal cancer.

Global mapping of Salmonella enterica-host protein-protein interactions during infection

The paper maps Salmonella enterica effector-host protein-protein interactions during infection, identifying 421 novel interactions and demonstrating their roles in pathogenesis.

Effect of Sec61 interaction with Mpd1 on Endoplasmic Reticulum-Associated Degradation

The paper identifies Mpd1 as an ERAD factor that interacts with Sec61 and shows that this interaction is required for CPY* ERAD.