Author

G. Thompson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 4 Pharmacology & Toxicology· 2 Biochemistry· 1 Ecology· 1 Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 8 Research Focus:host-pathogen & immune response· 5 Research Focus:cell type annotation· 2 Assay:DNA methylation· 2 Organism:human· 2 Assay:behavioral assay· 1 Research Focus:benchmarking· 1 Approach:comparative / phylogenetic analysis· 1

Frequent Co-Authors

A. Christopoulos· 2 shared C. Valant· 2 shared C. W. Lindsley· 2 shared D. M. Thal· 2 shared E. T. van der Westhuizen· 2 shared W. A. C. Burger· 2 shared Z. Vuckovic· 2 shared A. B. Lawrence· 1 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPharmacology & Toxicology

A. Christopoulos

Mutual co-authors in cluster

Author profile →

10 papers

Recent·Most cited

The CcpNmr Analysis Simulated Metabolomics Database (CASMDB): An Open-Source Collection of Metabolite Annotation Data for 1D 1H NMR-Based Metabolomics

M. W. Hayward, L. G. Mureddu, G. Thompson, M. Phelan, E. J. Brooksbank, G. W. Vuister

The paper describes the creation of CASMDB, a database of metabolite annotations for 1D 1H NMR-based metabolomics, enabling accurate simulation and visualization of spectra.

bioRxiv · May 5, 2024 · PreprintBiochemistry

5-ASA can functionally replace Clostridia to prevent a post-antibiotic bloom of Candida albicans by maintaining epithelial hypoxia

H. P. Savage, D. J. Bays, M. A. F. Gonzalez, E. J. Bejarano, H. Nguyen, H. L. P. Masson, T. P. Carvalho, R. L. Santos, G. Thompson, A. J. Bäumler

This study shows that 5-ASA can replace Clostridia to prevent Candida albicans overgrowth by restoring epithelial hypoxia after antibiotic treatment.

bioRxiv · Apr 17, 2023 · PreprintMicrobiology

Pharmacological hallmarks of allostery at the M4 muscarinic receptor elucidated through structure and dynamics

Z. Vuckovic, J. Wang, V. Pham, J. I. Mobbs, M. J. Belousoff, A. Bhattarai, W. A. C. Burger, G. Thompson, M. Yeasmin, K. Leach, E. T. van der Westhuizen, E. Khajehali, Y.-L. Liang, A. Glukhova, D. Wootten, , D. M. Thal

The paper presents cryo-EM structures of the M4 mAChR with ligands and modulators, revealing structural and dynamic insights into allosteric modulation and receptor activation mechanisms.

bioRxiv · Sep 27, 2022Pharmacology & Toxicology

Enhanced flavour profiles through radicicol induced genomic variation in S. pastorianus lager yeast

R. de la Cerda, G. Thompson, P. Zhang, K. Hokamp, F. Roche, S. Carlin, U. Vrhovsek, U. M. Bond

This study enhances flavour profiles in S. pastorianus lager yeast by inducing genomic variation through radicicol-mediated aneuploidy and selection for aromatic amino acid production.

bioRxiv · May 17, 2022 · PreprintMicrobiology

Characterization of the growth and morphology of a BSL-2 Coccidioides posadasii strain that persists in the parasitic life cycle at ambient CO2.

J. A. Garcia, K. Vu, G. Thompson, A. Gelli

This study characterizes a Coccidioides posadasii strain that maintains parasitic morphology at ambient CO2 and shows hyphal growth under spherule-inducing conditions.

bioRxiv · Mar 29, 2022Microbiology

Stem cell-derived macrophages as a new platform for studying host-pathogen interactions in livestock

S. Meek, T. Watson, L. Eory, G. McFarlane, F. J. Wynne, S. McCleary, L. E. M. Dunn, E. M. Charlton, C. Craig, B. Shih, T. Regan, R. M. Taylor, L. Sutherland, A. Gossner, C. Chintoan-Uta, , T. Burdon

The paper uses stem cell-derived macrophages from livestock to study host-pathogen interactions, showing they can be infected by important viruses and genetically modified.

bioRxiv · Sep 10, 2021Immunology

Localization and Functional Characterization of the Alternative Oxidase in Naegleria

D. Cantoni, A. O. Osborne, N. Taib, G. Thompson, E. Kazana, E. Edrich, I. R. Brown, S. Gribaldo, C. Gourlay, A. Tsaousis

The paper characterizes the localization and function of alternative oxidase in Naegleria species, showing its role in proliferation and potential pathogenicity.

bioRxiv · Sep 26, 2020 · PreprintMicrobiology

Crystal structure of the M5 muscarinic acetylcholine receptor

Z. Vuckovic, P. R. Gentry, A. E. Berizzi, K. Hirata, S. Varghese, G. Thompson, E. T. van der Westhuizen, W. A. C. Burger, R. Rahmani, C. Valant, C. J. Langmead, C. W. Lindsley, J. Baell, A. B. Tobin, P. M. Sexton, , D. M. Thal

The paper reports the crystal structure of the human M5 muscarinic acetylcholine receptor bound to tiotropium, revealing structural differences that inform ligand selectivity design.

bioRxiv · Aug 14, 2019Pharmacology & Toxicology

Strong population structure in Venezuelan populations of Coccidioides posadasii

M. M. Teixeira, P. Alvarado, C. Roe, G. Thompson, J. S. L. Patane, J. W. Sahl, P. Keim, J. N. Galgiani, A. P. Litvintseva, D. R. Matute, B. M. Barker

The paper identifies strong population structure and genetic differentiation in Coccidioides posadasii from Venezuela compared to North American populations, with evidence of admixture in Central America.

bioRxiv · Jul 30, 2019 · PreprintEvolutionary Biology

Alcohol increases aggression in flies

A. Park, T. Tran, E. Scheuermann, L. Gutierrez, C. Stojanik, J. Plyler, G. Thompson, D. Smith, N. S. Atkinson

The paper identifies two pathways by which alcohol increases aggression in male flies: one through enhancing an olfactory pheromone and the other through systemic alcohol effects.

bioRxiv · Jun 27, 2019 · PreprintEcology