Author

I. Lopez-Montero

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:host-pathogen & immune response· 2 Assay:ATAC-seq· 1 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

J. A. Enriquez· 2 shared P. Hernansanz-Agustin· 2 shared A. Bogdanova· 1 shared A. Cogolludo· 1 shared A. Cortes· 1 shared A. Izquierdo-Alvarez· 1 shared A. Martinez-del-Pozo· 1 shared A. Martinez-Ruiz· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersBiochemistry

J. A. Enriquez

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Na+/H+ antiporter activity by respiratory complex I controls mitochondrial Δ{psi} and is impaired in LHON disease

P. Hernansanz-Agustin, C. Morales-Vidal, E. Calvo, P. Natale, Y. Marti-Mateos, S. Jaroszewicz, J. L. Cabrera-Alarcon, I. Lopez-Montero, J. Vazquez, J. A. Enriquez

The paper identifies the P-module of complex I as the Na+/H+ antiporter in mitochondria, showing its role in maintaining ΔΨmt and its dysfunction in LHON disease.

bioRxiv · May 30, 2023 · PreprintBiochemistry

Reducing Cholesterol in Resting Macrophage Activates NF-kB through Mitochondria, Resulting in Epigenomic Reprogramming to Dampen Inflammation in Activated Macrophages

X. Zha, Z. Salloum, K. Dauner, K. Nakka, N. Verma, H. Bandukwala, A. Sorisky, J. Dilworth, D. V. Gonzalez, V. A. Vedia, I. Lopez-Montero, J. McDonald, C. D. Corley

bioRxiv · Feb 10, 2022 · PreprintCell Biology

Mitochondrial Na+ controls oxidative phosphorylation and hypoxic redox signalling

P. Hernansanz-Agustin, C. Choya-Foces, S. Carregal-Romero, E. Ramos, T. Oliva, T. Villa-Pina, L. Moreno, A. Izquierdo-Alvarez, J. D. Cabrera-Garcia, A. Cortes, A. V. Lechuga-Vieco, P. Jadiya, E. Navarro, E. Parada, A. Palomino-Antolin, , A. Martinez-Ruiz

This study shows that mitochondrial Na+ acts as a second messenger regulating OXPHOS and ROS production through interactions with phospholipids during hypoxia.

bioRxiv · Oct 31, 2019Biochemistry