I. Salinas

The telencephalon is a neuronal substrate for systemic inflammatory responses in teleosts via polyamine metabolism

The paper identifies the telencephalon as a neuronal substrate for systemic inflammatory responses in teleosts, showing polyamine metabolism changes and behavioral fever responses.

A niche-adapted brain microbiome in salmonids at homeostasis

The paper identifies a resident bacterial community in the brains of healthy salmonids and shows its relationship to gut and blood microbiomes, with adaptations for brain colonization.

Identification of a new pharyngeal mucosal lymphoid organ in zebrafish and other teleosts: tonsils in fish?

The study identifies a new mucosal lymphoid organ in zebrafish and other teleosts, analogous to mammalian tonsils, and describes its structure and immune function.

Ontogeny of the organized nasopharynx-associated lymphoid tissue in rainbow trout

This study identifies the developmental sequence of organized nasopharynx-associated lymphoid tissue (O-NALT) in rainbow trout, showing CD8+ T cells initiate its formation and that O-NALT is fully formed by 1400DD, marking a potential earliest time for effective mucosal vaccination.

Signal Improved ultra-Fast Light-sheet Microscope (SIFT) for large tissue imaging

The paper introduces an improved light-sheet microscope that increases imaging speed and signal strength for large tissue samples.

Peripheral detection of viruses shapes brain immunity and behavior in zebrafish

This study shows that viral detection by olfactory sensory neurons in zebrafish triggers neuroimmune responses and behavioral changes through PACAP signaling in the olfactory bulb.

Secretory IgM (sIgM) is an ancient master regulator of microbiota homeostasis and metabolism

This study shows that IgM, not just sIgA and sIgT, is essential for microbiota homeostasis and metabolism in vertebrates, challenging the current understanding of sIg roles.

Exploring zebrafish larvae as a COVID-19 model: probable SARS-COV-2 replication in the swim bladder

This study tests SARS-CoV-2 replication in zebrafish larvae, finding limited infection except in the swim bladder, which shows some viral RNA and nucleoprotein expression.

Effects of ploidy and salmonid alphavirus infection on the skin and gill microbiome of Atlantic salmon (Salmo salar)

This study compares the skin and gill microbiome of diploid and triploid Atlantic salmon, finding ploidy affects gill microbiome diversity and susceptibility to pathogens.

A zebrafish model for COVID-19 recapitulates olfactory and cardiovascular pathophysiologies caused by SARS-CoV-2

This study uses zebrafish models to replicate SARS-CoV-2-induced olfactory and cardiovascular effects, showing drug treatment can reverse some symptoms.

Olfactory sensory neurons mediate ultra-rapid antiviral immune responses in teleosts in a TrkA-dependent manner

This study shows that olfactory sensory neurons in teleosts detect viruses via TrkA receptor interaction, triggering local immune responses and reducing systemic inflammation.

Analysis of the gut and gill microbiome of resistant and susceptible lines of rainbow trout (Oncorhynchus mykiss)

This study compares the gut and gill microbiomes of resistant and susceptible rainbow trout lines to assess the impact of selective breeding on microbial diversity and potential pathogen abundance.

Mucosal immunoglobulins protect the olfactory organ of teleost fish against parasitic infection

This study investigates nasal immune responses in rainbow trout to Ichthyophthirius multifiliis infection, finding parasite-specific IgT production and B-cell proliferation in the nasal mucosa.