K. Miyazawa

Stratification of viral shedding patterns in saliva of COVID-19 patients

This study stratifies SARS-CoV-2 viral shedding patterns in saliva into three groups with distinct durations using a mathematical model and clustering, but finds no clear clinical or miRNA biomarkers explaining the differences.

Delayed localization of A-type lamins to the rupture sites in Hutchinson-Gilford progeria syndrome

This study investigates the delayed localization of A-type lamins to nuclear envelope rupture sites in HGPS, identifying farnesylation and proteolytic cleavage as key factors affecting this process.

Cleavage of α-1,4-Glycosidic Linkages by the Glycosylphosphatidylinositol-Anchored α-Amylase AgtA Decreases the Molecular Weight of Cell Wall α-1,3-Glucan in Aspergillus oryzae

This study shows that AoAgtA, a GPI-anchored α-amylase in Aspergillus oryzae, cleaves -1,4-glycosidic bonds in the spacer region of cell wall -1,3-glucan, reducing its molecular weight.

A glycosylphosphatidylinositol-anchored α-amylase encoded by amyD contributes to a decrease in the molecular mass of cell wall α-1,3-glucan in Aspergillus nidulans

The paper investigates the role of AmyD, a GPI-anchored α-amylase, in regulating the molecular mass of -1,3-glucan in Aspergillus nidulans cell walls.

SMAD3 Determines Conventional versus Plasmacytoid Dendritic Cell Fates

This study identifies SMAD3 as a key regulator determining conventional DC versus plasmacytoid DC differentiation through distinct gene regulatory mechanisms.

Addiction of mesenchymal phenotypes on the FGF/FGFR axis in oral squamous cell carcinoma cells

This study shows that autocrine FGF-FGFR(IIIc) signaling sustains ZEB1/2 expression and mesenchymal phenotypes in oral squamous cell carcinoma cells.

Both galactosaminogalactan and α-1,3-glucan contribute to aggregation of Aspergillusoryzae hyphae in liquid culture

This paper identifies galactosaminogalactan and α-1,3-glucan as factors contributing to hyphal aggregation in Aspergillus oryzae and shows that their removal disperses hyphae, improving recombinant protein production.