Author

J. A. Whitson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:metabolism & bioenergetics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

P. S. Rabinovitch· 3 shared D. J. Marcinek· 2 shared M. D. Campbell· 2 shared M. T. Sweetwyne· 2 shared A. M. Rountree· 1 shared A. P. Valencia· 1 shared B. C. Jenkins· 1 shared B. M. Robbings· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersPhysiology

P. S. Rabinovitch

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3 papers

Recent·Most cited

Metabolite accumulation from oral NMN supplementation drives aging-specific kidney inflammation

T. A. Saleh, J. A. Whitson, P. Keiser, P. Prasad, B. C. Jenkins, T. Sodeinde, C. Mann, P. S. Rabinovitch, M. R. McReynolds, M. T. Sweetwyne

This study shows that NMN supplementation in aged mice increases kidney inflammation and uremic toxins, suggesting age-specific risks of NAD+ boosting supplements.

bioRxiv · Apr 9, 2024 · PreprintPhysiology

Elamipretide (SS-31) Treatment Attenuates Age-Associated Post-Translational Modifications of Heart Proteins

J. A. Whitson, M. Martin-Perez, T. Zhang, M. J. Gaffrey, G. E. Merrihew, E. Huang, C. C. White, T. J. Kavanagh, W.-J. Qian, M. D. Campbell, M. J. MacCoss, D. J. Marcinek, J. Villen, P. S. Rabinovitch

This study investigates how elamipretide affects age-related post-translational modifications in mouse heart proteins, finding that it reverses oxidative changes but not phosphorylation changes.

bioRxiv · Aug 6, 2021Cell Biology

Metabolic function in aging retina and retinal pigment epithelium remains robust despite vision loss

K. A. Tsantilas, W. M. Cleghorn, C. M. Bisbach, J. A. Whitson, D. T. Hass, B. M. Robbings, M. Sadilek, J. D. Linton, A. M. Rountree, A. P. Valencia, M. T. Sweetwyne, M. D. Campbell, H. Zhang, C. S. R. Jankowski, I. R. Sweet, , J. B. Hurley

This study examines metabolic changes in aging mouse retina and eyecup, finding stable glucose and glutamine metabolism despite vision loss.

bioRxiv · Apr 6, 2021Biochemistry