J. Choi

The paper mathematically shows that reversed Trivers-Willard theory can result from parental fitness optimization, depending on the fitness functions used.

The paper shows that tyrosine phosphorylation regulates Daple-PARD3 complex assembly at cell-cell junctions, influencing planar cell polarity during migration.

The paper identifies gene networks and eQTLs associated with platinum-based chemotherapy response in high-grade serous ovarian cancer using TCGA data.

The paper reconstructs a Genome Tree of Life using proteome data from over 4000 organisms, suggesting a 'Deep Burst' of early life diversification into prokarya and eukarya.

This study evaluates seven computational methods for inferring clone phylogenies from bulk sequencing data, finding significant variation in their accuracy for mutation order and clone grouping.

MATE-Seq identifies antigen-specific T-cell receptors by isolating and sequencing T-cells bound to peptide-MHC tetramers with high sensitivity.

The paper describes an educational workshop series aimed at teaching microbiologists computing skills for microbiome analysis over five years.

The paper investigates how eIF5B facilitates the transition from translation initiation to elongation in yeast using single-molecule fluorescence microscopy.

This study investigates RACK1's exchange dynamics on and off the ribosome using fluorescent labeling and biochemical analyses, showing its stable binding and limited conformational changes.

This study shows that tumor acidity promotes prostate cancer by altering macrophage phenotype, both in vitro and in vivo, and is supported by in silico modeling.

This study identifies miR-10b as a mediator of BRafV600E-driven anchorage-independent growth and invasion in melanoma cells.

This study shows that RIG-I activates autophagy via the MAVS-TRAF6-Beclin-1 axis to control viral replication and limit excessive interferon response.

The paper identifies a mechanosensitive pathway, SCWISh, essential for yeast survival under mechanical pressure by integrating signals from the SMuSh and CWI pathways.

This study shows that intestinal crypts rapidly recover from focal damage through coordinated stem cell motion, which is impaired by aging.

This study shows that the FACT complex facilitates DME-mediated DNA demethylation at heterochromatin during Arabidopsis reproduction by enabling access to GC-rich, nucleosome-dense regions.