J. Dong

This paper determines the structures of two antibodies in the AZD7442 cocktail that neutralize SARS-CoV-2 and identifies critical residues for neutralization and viral escape.

The paper identifies common genetic and structural features of human antibodies recognizing the influenza HA trimer interface, suggesting it as a target for vaccine design.

This study analyzes 3,920 rodent models of NAFLD, finding adipose dysfunction and innate immune perturbation are key factors, and high-fat, high-fructose diets best mimic human NAFLD.

The paper investigates photosynthesis-related gene expression in albino Artocarpus heterophyllus seedlings, finding down-regulated genes in pigment synthesis and photosynthesis pathways.

This study identifies a viral protein translation mechanism involving mitochondrial machinery and highlights mitochondria as a target for antiviral drug development.

This study shows that influenza A virus pre-infection increases SARS-CoV-2 infectivity in multiple cell types and worsens lung damage in mice.

The paper identifies BSL protein phosphatase polarization as a spatiotemporal molecular switch governing asymmetric cell division in Arabidopsis stomatal stem cells.

This study develops a cell-based chimeric vaccine against SARS-CoV-2 that induces strong T cell immunity and neutralizing antibodies without toxicity.

This study identifies GCN5 as a mediator of transcriptional de-repression and genomic instability in plants lacking H3.1K27me1, revealing its role in maintaining genome stability through histone acetylation regulation.

The paper shows that tissue-resident memory CD4+ T cells mobilize into the blood after vaccination and contribute to systemic secondary immune responses.

The study identifies AD1, a 3-KETOACYL-CoA SYNTHASE gene regulated by FUSED LEAVES1, as essential for cuticle formation and organ separation in maize.

This paper meta-analyzes rodent studies on NAFLD treatments, finding limited efficacy and high bias, suggesting challenges in translating animal results to human therapies.

The paper shows that phyB induces alternative splicing of PIF3, leading to intron retention in the 5UTR and uORF-mediated translational inhibition, regulated by the short-day diurnal cycle.

This study shows that fibroblast-specific IL11 signaling is critical for lung fibrosis and that inflammation can result from stromal activation rather than being a primary driver.

This study identifies the Sam50-Mic19-Mic60 axis as critical for mitochondrial cristae architecture by connecting SAM and MICOS complexes through OMA1-mediated cleavage of Mic19.

The paper identifies the plant-specific BRX family as partners of BASL in establishing cell fate asymmetry in Arabidopsis stomatal lineage through polar localization and mutual dependencies.

This study shows that chicken RB1 inhibits preadipocyte proliferation by affecting the G1/S cell cycle transition.

The paper identifies MISTERMINATE as a mechanism linking mitochondrial dysfunction to proteostasis failure through translational termination impairment and C-terminal extension of mitochondrial proteins.

This study heterologously expresses Stlac2 from Setosphaeria turcica and demonstrates its ability to decolorize malachite green with high efficiency.

This study enhances methyl ketone production in Pseudomonas putida using plant-derived amino acids from hydrolysates, achieving a 9-fold increase in titer.

This paper engineers non-pathogenic E. coli to detect ETEC using quorum sensing and cellulose encapsulation for environmental monitoring.

This study develops a multi-hierarchical nano-SAR assessment for Fe2O3 nanomaterials, revealing how their properties influence bio-effects like cell migration and inflammation.