J. He

This study analyzes the impact of socio-economic factors on surface water quality at provincial boundaries in China, identifying key factors affecting water quality.

This study identifies a potent human monoclonal antibody, 35B5, that neutralizes SARS-CoV-2 and its variants by targeting a conserved epitope on the RBD, offering a potential therapeutic and vaccine design strategy.

This study shows that humanized mice can be infected by SARS-CoV-2, leading to immune responses and immunopathology, providing a model for studying the virus and testing therapies.

The paper identifies a wound-like tumor periphery in breast cancer as a uniparameter marker predicting multidrug nonresponse and poor prognosis across molecular subtypes.

This study identifies quantitative trait loci (QTLs) associated with vegetative phase change in Arabidopsis thaliana accessions, revealing distinct genetic mechanisms for different developmental transitions.

The paper isolates and characterizes two novel photosystem I supercomplexes from cyanobacteria, revealing the structure of the PSI octamer at near-atomic resolution.

This study shows drought reduces sucrose transport from cottonseed coat to fiber and disrupts sucrose allocation, leading to decreased cellulose synthesis and fiber strength.

The paper identifies ERN1, a G-lectin receptor kinase, as a negative regulator of Arabidopsis immunity against root-knot nematodes by suppressing defense responses.

The paper uses spatial transcriptomics to identify antiparasitic targets in Brugia malayi head tissues, revealing new drug and vaccine candidates.

This study examines how cannabinoids affect ethanol-related behaviors and developmental outcomes in Drosophila, finding differential effects on tolerance and developmental defects.

This study shows ASH1L's enzymatic activity is essential for MLL-AF9-induced leukemogenesis by enhancing target gene expression through histone modification.

This study shows that STAT3 deficiency in dendritic cells leads to colitis in mice, which is dependent on the gut microbiome.

This study uses silica-dried leaf tissues for RNA-seq and phylotranscriptomic analysis, showing they are viable for phylogenomic studies with results comparable to liquid nitrogen-preserved samples.

A toolset for simultaneous imaging of Ca2+ dynamics in subcellular compartments has uncovered unrecognized Ca2+ signatures in Arabidopsis cells in response to developmental and external cues.

This study profiles the tumor immune microenvironment of NSCLC using multiplex immunofluorescence, identifying three immune subtypes and an immune-related risk score for prognosis prediction.

This study examines how nitrification inhibitors and straw incorporation affect N2O emissions and microbial communities in different cropland soils, finding that their effects vary by soil type.

This study identifies a p53-like transcription activation domain in PIF3 and shows that PHYB binding inhibits its activity, revealing a photoresponsive transcriptional switch in Arabidopsis.

The paper shows that Clp protease and AscarD regulate CarD levels to help mycobacteria survive starvation by reducing rRNA synthesis.

This paper uses Maxent modeling to predict the global distribution of talaromycosis, identifying key environmental and epidemiological drivers.

The paper develops a miniaturized aerosol sampling device inspired by wet scrubbers, demonstrating efficient aerosol capture and viability retention of bioaerosols.

Analysis of multiple tmk mutants reveals key roles of TMKs in plant development, including organogenesis, leaf size, fertility, and selfing population defects.

This study shows VAL genes regulate vegetative phase change through both miR156-dependent and independent mechanisms in plants.

This study evaluates enzalutamide's antiviral efficacy against SARS-CoV-2 in different cell types and mouse models, finding it effective in prostate cancer cells but not in lung cells or organoids.

This study shows cannabinoids affect food preference and consumption in Drosophila without requiring cannabinoid receptors, with some inhibiting intake and others promoting starvation resistance.

This study identifies immune markers, including HLA-DR and CTLA-4 expression on CD4 T cells, that predict HBsAg loss in chronic hepatitis B patients.

This study investigates the role of YAP1 in TNF-α-induced proliferation and osteogenic differentiation of human periodontal ligament stem cells, finding that YAP1 enhances cell proliferation and differentiation via the Hippo signaling pathway.

The paper identifies ERG's role in prostate cancer by showing it inhibits basal cell differentiation through chromatin interactions, promoting luminal cell fate.

The paper develops scAAVengr, a single-cell pipeline to quantify AAV gene expression efficiency in non-human primate retina, demonstrating its utility with a top-performing AAV variant.