Injectable Nanoparticle-Based Hydrogels Enable the Safe and Effective Deployment of Immunostimulatory CD40 Agonist Antibodies
S. Correa, E. C. Gale, A. T. Mayer, Z. Xiao, C. Liong, J. H. Klich, R. A. Brown, E. L. Meany, O. M. Saouaf, C. L. Maikawa, A. K. Grosskopf, J. L. Mann, J. Idoyaga, E. Appel
This paper develops injectable hydrogels to safely deliver CD40 agonist antibodies, reducing toxicity while maintaining anti-cancer efficacy in a melanoma model.
bioRxiv · Jun 27, 2021Bioengineering