Author

O. M. Saouaf

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 4

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 4 Approach:experimental assay· 4 Organism:mouse· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

E. Appel· 4 shared B. S. Ou· 3 shared J. Yan· 3 shared E. C. Gale· 2 shared J. Baillet· 2 shared A. E. Powell· 1 shared A. K. Grosskopf· 1 shared A. Nejatfard· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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4 shared papersBioengineering

E. Appel

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A regimen compression strategy for commercial vaccines leveraging an injectable hydrogel depot technology for sustained vaccine exposure

J. Yan, B. S. Ou, O. M. Saouaf, E. Meany, N. Eckman, E. Appel

This paper develops an injectable hydrogel depot technology for sustained rabies vaccine delivery, showing a single dose can match a standard prime-boost regimen in mice.

bioRxiv · Mar 23, 2023Bioengineering

Nanoparticle-Conjugated TLR9 Agonists Improve the Potency, Durability, and Breadth of COVID-19 Vaccines

B. S. Ou, J. Baillet, V. C. T. M. Picece, E. C. Gale, A. E. Powell, O. M. Saouaf, J. Yan, A. Nejatfard, H. Lopez Hernandez, E. Appel

This paper develops CpG nanoparticle adjuvants that enhance the potency, durability, and breadth of COVID-19 vaccines by improving antigen delivery and immune response.

bioRxiv · Jan 2, 2023 · PreprintBioengineering

Broad and Durable Humoral Responses Following Single Hydrogel Immunization of SARS-CoV-2 Subunit Vaccine

B. S. Ou, O. M. Saouaf, J. Yan, T. U. J. Bruun, J. Baillet, X. Zhou, N. P. King, E. Appel

This study develops a single-dose SARS-CoV-2 subunit vaccine using hydrogel technology that generates rapid, broad, and durable humoral immunity compared to traditional multi-dose regimens.

bioRxiv · Dec 12, 2022Bioengineering

Injectable Nanoparticle-Based Hydrogels Enable the Safe and Effective Deployment of Immunostimulatory CD40 Agonist Antibodies

S. Correa, E. C. Gale, A. T. Mayer, Z. Xiao, C. Liong, J. H. Klich, R. A. Brown, E. L. Meany, O. M. Saouaf, C. L. Maikawa, A. K. Grosskopf, J. L. Mann, J. Idoyaga, E. Appel

This paper develops injectable hydrogels to safely deliver CD40 agonist antibodies, reducing toxicity while maintaining anti-cancer efficacy in a melanoma model.

bioRxiv · Jun 27, 2021Bioengineering