The mechanism of selective kinesin inhibition by kinesin binding protein.
J. Atherton, J. J. A. Hummel, N. Olieric, J. Locke, A. Pena, S. S. Rosenfeld, M. O. Steinmetz, C. C. Hoogenraad, C. A. Moores
This study identifies how kinesin binding protein selectively inhibits specific kinesins by structurally distorting their motor domains and blocking microtubule attachment.
bioRxiv · Jul 17, 2020 · PreprintBiochemistry