Author

Jan Tavernier

Vlaams Instituut voor Biotechnologie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Immunology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Assay:protein structure· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:matrix factorization· 1 Organism:mouse· 1

Frequent Co-Authors

DAVID EDWIN HILLiD· 3 shared Irma H. LemmensiD· 3 shared Jean‐Claude TwizereiD· 3 shared Kerstin SpirohniD· 3 shared Marc VidaliD· 3 shared Michael A. CalderwoodiD· 3 shared Tong HaoiD· 3 shared Aaron D. Richardson· 2 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMolecular Biology

DAVID EDWIN HILLORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A novel tumor-targeted interferon-α/-β receptor 1 antagonist increases replication of oncolytic vesicular stomatitis virus in a mouse mesothelioma model

Thomas Teja Ogor, Yann Bordat, Manon Souchard, Joëlle S. Nader, Geneviève Garcin, Camille Chatelain, Virginie Dehame, Sophie Deshayes, Lucas Treps, Mar Naranjo‐Gómez, Nicolas Boisgerault, Jan Tavernier, Mireia Pelegrín, Jean‐François Fonteneau

This paper develops IFNAR1 antagonists that selectively block IFNAR signaling in tumor cells, enhancing VSV oncolytic activity in mesothelioma and melanoma models.

bioRxiv · Jun 3, 2026 · PreprintImmunology

Dynamic engagement of dual-role regulators by the Sin3 complex

Julien Olivet, Neesha Rajesh Shewakramani, Joseph Cesare, Florent Laval, Jules Nde, Jasper Van de Veire, Yasmine Brammerloo, Bastien Brebel, Olivia Debnath, Aaron D. Richardson, Hong Yue, Yang Wang, Kerstin Spirohn, Irma H. Lemmens, Tong Hao, , Kalyan Das

The paper investigates how dual-role regulators interact with the Sin3 complex using structural and functional analyses, revealing mechanisms for transcriptional crosstalk.

bioRxiv · Feb 26, 2026 · PreprintMolecular Biology

Expanding the HDAC druggable landscape beyond enzymatic activity

Julien Olivet, Soon Gang Choi, Salvador Sierra, Tina M. O’Grady, Mario de la Fuente Revenga, Florent Laval, Vladimir V. Botchkarev, Christoph Gorgulla, Paul W. Coote, Jérémy Blavier, Ezekiel A. Geffken, Jimit Lakhani, Kijun Song, Zoe C. Yeoh, Bin Hu, , Marc Vidal

This paper identifies a non-enzymatic HDAC inhibitor with anti-tumor and anti-psychedelic effects, showing reduced gene modulation compared to enzymatic inhibitors.

bioRxiv · Dec 7, 2022 · PreprintMolecular Biology

Binary Interactome Models of Inner- Versus Outer-Complexome Organization

Luke Lambourne, Anupama Yadav, Yang Wang, Alice Desbuleux, Dae‐Kyum Kim, Tiziana M. Cafarelli, Carles Pons, István A. Kovács, Noor Jailkhani, Sadie Schlabach, David De Ridder, Katja Luck, Wenting Bian, Yun Shen, Zhipeng Yang, , Marc Vidal

The paper constructs a high-quality yeast binary interactome map and compares inner- and outer-complexome organization, finding the outer-complexome contains more interactions and exhibits higher functional heterogeneity.

bioRxiv · Mar 16, 2021 · PreprintSystems Biology