Author

K. M. Ng

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Biophysics· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:bacteria (other)· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:imaging· 2 Assay:metagenomics· 2

Frequent Co-Authors

K. C. Huang· 4 shared C. Tropini· 3 shared A. Aranda-Diaz· 2 shared D. M. Pepin· 2 shared F. B. Yu· 2 shared J. C. Burckhardt· 2 shared K. B. Xavier· 2 shared S. K. Higginbottom· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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4 shared papersMicrobiology

K. C. Huang

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Author profile →

7 papers

Recent·Most cited

PUPpy: a primer design pipeline for substrain-level microbial detection and absolute quantification.

H. Ghezzi, M. Y. Fan, K. M. Ng, J. C. Burckhardt, D. M. Pepin, X. Lin, R. M. Ziels, C. Tropini

PUPpy designs taxon-specific primers for substrain-level microbial detection and absolute quantification, outperforming 16S rRNA and shotgun sequencing in defined communities.

bioRxiv · Dec 18, 2023Microbiology

Tumor cell heterogeneity drives spatial organization of the intratumoral immune response in squamous cell skin carcinoma

M. Tanaka, L. Lum, K. H. Hu, C. Ledezma-Soto, B. Samad, D. A. Superville, K. M. Ng, Z. Adams, K. H. Kersten, L. Fong, A. Combes, M. F. Krummel, M. Q. Reeves

This study shows that tumor cell heterogeneity influences the spatial organization of immune responses in squamous cell skin carcinoma, affecting immunotherapy outcomes.

bioRxiv · Apr 25, 2023 · PreprintCancer Biology

Single-strain behavior predicts responses to environmental pH and osmolality in the gut microbiota.

K. M. Ng, S. Pannu, S. Liu, J. C. Burckhardt, T. Hughes, W. Van Treuren, J. Nguyen, K. Naqvi, B. Nguyen, C. A. Clayton, D. M. Pepin, S. R. Collins, C. Tropini

This study predicts microbiota responses to environmental pH and osmolality by analyzing bacterial growth under controlled conditions and identifying predictive genes and pathways.

bioRxiv · Aug 31, 2022Microbiology

Quantifying the interplay between rapid bacterial evolution within the mouse intestine and transmission between hosts

K. S. Vasquez, L. Willis, N. Cira, K. M. Ng, M. F. Pedro, A. Aranda-Diaz, M. Rajendram, F. B. Yu, S. K. Higginbottom, N. Neff, G. Sherlock, K. B. Xavier, S. Quake, J. Sonnenburg, B. H. Good, K. C. Huang

The paper tracks bacterial evolution and transmission in mice using barcoded E. coli strains, showing rapid selection and migration effects on microbiota composition.

bioRxiv · Dec 4, 2020Microbiology

Entropy-driven translocation of disordered proteins through the Gram-positive bacterial cell wall

D. K. Halladin, F. E. Ortega, K. M. Ng, M. J. Footer, N. S. Mitic, S. N. Malkov, A. Gopinathan, K. C. Huang, J. A. Theriot

The paper shows that entropy drives disordered proteins through Gram-positive bacterial cell walls, using a physical model and experimental validation.

bioRxiv · Nov 24, 2020Biophysics

Recovery of the gut microbiota after antibiotics depends on host diet and environmental reservoirs

K. M. Ng, A. Aranda-Diaz, C. Tropini, M. R. Frankel, W. W. Van Treuren, C. O'Laughlin, B. D. Merrill, F. B. Yu, K. M. Pruss, R. A. Oliveira, S. K. Higginbottom, N. F. Neff, M. A. Fischbach, K. B. Xavier, J. L. Sonnenburg, K. C. Huang

The paper investigates how gut microbiota recovers after antibiotics, showing diet and environmental factors influence resilience and recovery patterns.

bioRxiv · Aug 8, 2019Microbiology

Mechanically Resolved Imaging of Bacteria using Expansion Microscopy

Y. Lim, M. Khariton, K. M. Lane, A. L. Shiver, K. M. Ng, S. R. Bray, J. Qin, K. C. Huang, B. Wang

This paper introduces expansion microscopy to distinguish bacterial species and detect phenotypic changes in dense microbial communities.

bioRxiv · Apr 29, 2019Biophysics