Author

K. Onuma

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:organoid / primary culture· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

M. Inoue· 4 shared J. Kondo· 3 shared K. Kawada· 2 shared K. Obama· 2 shared M. Kamada· 2 shared Y. Tanaka· 2 shared E. Hatano· 1 shared E. Miyoshi· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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4 shared papersCancer Biology

M. Inoue

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Ultra-Rapid and Specific Gelation of Collagen Molecules for Transparent and Tough Gels by Transition Metal Complexation

T. Suezawa, N. Sasaki, N. Assan, Y. Uetake, K. Onuma, H. Sakurai, R. Katayama, M. Inoue, M. Matsusaki

This paper develops a method to rapidly form transparent and tough collagen gels using transition metal complexation, enabling deep-live cell observation in a mechanically tunable environment.

bioRxiv · Mar 21, 2023Bioengineering

Inhibition of the BMP pathway suppresses tumor growth via downregulation of EGFR in MEK/ERK-dependent colorectal cancer

S. Shimizu, J. Kondo, K. Onuma, K. Ota, M. Kamada, Y. Harada, Y. Tanaka, M. Adachi Nakazawa, Y. Tamada, Y. Okuno, K. Kawada, K. Obama, R. J. Coffey, Y. Fujiwara, M. Inoue

This study shows that inhibiting the BMP pathway suppresses colorectal cancer growth by reducing EGFR, and combining BMP and MEK inhibition enhances therapeutic effects in patient-derived organoids.

bioRxiv · Nov 1, 2022 · PreprintCancer Biology

Hepatocyte Differentiation From Mouse Liver Ductal Organoids By Transducing Four Liver-Specific Transcription Factors

K. Tomofuji, J. Kondo, K. Onuma, K. Oyama, E. Miyoshi, K. Fukumitsu, T. Ishii, E. Hatano, M. Inoue

This study identifies four transcription factors that enhance hepatocyte differentiation from liver ductal organoids, improving their functionality and reducing cholangiocyte characteristics.

bioRxiv · Aug 6, 2022 · PreprintCell Biology

Distinct and interchangeable growing patterns in colorectal cancer stem-like cells are regulated by Musashi-1

R. Coppo, J. Kondo, K. Iida, M. Okada, K. Onuma, Y. Tanaka, M. Kamada, M. Ohue, K. Kawada, K. Obama, M. Inoue

The paper identifies distinct growth patterns in colorectal cancer stem-like cells and shows Musashi-1 regulates their plasticity and drug resistance.

bioRxiv · Nov 25, 2021 · PreprintCancer Biology