Author

Y. Fujiwara

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Biochemistry· 1 Cancer Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:cell type annotation· 4 Research Focus:differential expression· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

M. Inoue· 2 shared A. H. Maglieri· 1 shared A. Hashimoto· 1 shared A. Sawada· 1 shared C. Kabuta· 1 shared D. Seruggia· 1 shared E. Inoue· 1 shared E. Manieri· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 6 mutual co-author links

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2 shared papersCancer Biology

M. Inoue

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

A novel mouse allele of the DNA/RNA helicase senataxin (Setxspcar3) causing meiotic arrest of spermatocytes and male infertility

Y. Fujiwara, K. Saito, F. Sun, E. Inoue, J. Schimenti, Y. Okada, M. A. Handel

This study identifies a new Setx allele causing male infertility and female subfertility in mice by disrupting meiosis and spermatogenesis through R-loop accumulation and DNA damage.

bioRxiv · Apr 12, 2023 · PreprintCell Biology

Defining the structure, signals, and cellular elements of the gastric mesenchymal niche

E. Manieri, G. Tie, D. Seruggia, S. Madha, A. H. Maglieri, K. Huang, Y. Fujiwara, K. Zhang, S. H. Orkin, N. McCarthy, R. A. Shivdasani

The paper identifies regional subpopulations and niche properties of gastric PDGFRA+ mesenchymal cells, revealing distinct roles in supporting corpus and antral organoids.

bioRxiv · Feb 11, 2023Cell Biology

Actin filaments accumulate in the nucleus during interphase and remain in the vicinity of condensing chromosomes during prophase to metaphase in zebrafish early embryos

H. Oda, Y. Sato, S. A. Kawashima, Y. Fujiwara, M. Palfy, E. Wu, N. L. Vastenhouw, M. Kanai, H. Kimura

bioRxiv · Nov 6, 2022 · PreprintCell Biology

Inhibition of the BMP pathway suppresses tumor growth via downregulation of EGFR in MEK/ERK-dependent colorectal cancer

S. Shimizu, J. Kondo, K. Onuma, K. Ota, M. Kamada, Y. Harada, Y. Tanaka, M. Adachi Nakazawa, Y. Tamada, Y. Okuno, K. Kawada, K. Obama, R. J. Coffey, Y. Fujiwara, M. Inoue

This study shows that inhibiting the BMP pathway suppresses colorectal cancer growth by reducing EGFR, and combining BMP and MEK inhibition enhances therapeutic effects in patient-derived organoids.

bioRxiv · Nov 1, 2022 · PreprintCancer Biology

Lysosomal microautophagic pathway links proteostasis to protein aggregation disease

Y. Fujiwara, C. Kabuta, V. R. Contu, M. Ogawa, H. Fujita, H. Kikuchi, R. Sakai, M. Suzuki, I. Koyama-Honda, M. Inoue, Y. Oya, Y. U. Inoue, T. Inoue, R. Takahashi, G. Matsumoto, , T. Kabuta

This study identifies SIDT2 as a mediator of microautophagy that delivers cytosolic proteins into lysosomes, linking proteostasis to protein aggregation disease.

bioRxiv · Aug 11, 2020 · PreprintCell Biology

Phosphorylation of Elovl5 changes its substrate preference to synthesize Mead acid in response to essential fatty acid deficiency

Y. Hayashi, M. Yamano, N. Kono, H. Arai, Y. Fujiwara, I. Ichi

bioRxiv · Jan 31, 2020 · PreprintBiochemistry

Changes in clock gene expression in esophagus in rat reflux esophagitis

A. Hashimoto, R. Uemura, A. Sawada, Y. Nadatani, K. Otani, S. Hosomi, Y. Nagami, F. Tanaka, N. Kamata, K. Taira, H. Yamagami, T. Tanigawa, T. Watanabe, Y. Fujiwara

This study examines how reflux esophagitis in rats affects circadian clock gene expression in the esophagus and other organs, finding disrupted circadian variability in several genes during acute and chronic phases.

bioRxiv · Dec 6, 2018Pathology