Author

K.-B. Kim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 6 Cell Biology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:mouse· 7 Research Focus:cell type annotation· 5 Research Focus:cancer & tumor microenvironment· 4 Organism:human· 4 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Assay:bulk RNA-seq· 2

Frequent Co-Authors

K.-S. PARK· 8 shared D.-W. Kim· 4 shared J.-I. Park· 3 shared B. Kim· 2 shared G. Zou· 2 shared J. Zhang· 2 shared K.-P. Ko· 2 shared S. Jun· 2 shared

Activity by Year

2020-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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8 shared papersCancer Biology

K.-S. PARK

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

CRACD suppresses neuroendocrinal plasticity of lung adenocarcinoma

B. Kim, S. Zhang, Y. Huang, K.-P. Ko, G. Zou, J. Zhang, S. Jun, K.-B. Kim, Y.-S. Jung, K.-S. PARK, J.-I. Park

This study shows CRACD suppresses neuroendocrinal plasticity in lung adenocarcinoma by restricting cell de-differentiation and stemness-related pathways.

bioRxiv · Apr 19, 2023 · PreprintCancer Biology

Actin dysregulation induces neuroendocrine plasticity and immune evasion: a vulnerability of small cell lung cancer

Y. Seo, S. Zhang, J. Jang, K.-P. Ko, K.-B. Kim, Y. Huang, D.-W. Kim, B. Kim, G. Zou, J. Zhang, S. Jun, W. Chu, N. A. Kirk, Y. E. Hwang, Y. H. Ban, , J.-I. Park

This study shows that CRACD, an actin regulator, suppresses neuroendocrine plasticity and immune evasion in SCLC by modulating NOTCH1 and EZH2 pathways, suggesting EZH2 blockade as a potential therapy.

bioRxiv · Feb 15, 2023Cancer Biology

Opa1 and Drp1 reciprocally regulate cristae morphology, ETC function, and NAD+ regeneration in KRas-mutant lung adenocarcinoma

D. T. Sessions, K.-B. Kim, J. A. Kashatus, N. Churchill, K.-S. Park, M. W. Mayo, H. Sesaki, D. F. Kashatus

This study shows that Opa1, not Drp1, is critical for maintaining ETC function and NAD+ regeneration in KRas-mutant lung adenocarcinoma, with Opa1 deletion inhibiting tumor growth.

bioRxiv · Jun 1, 2022Cell Biology

WNT5A-RHOA axis is a new vulnerability in small-cell lung cancer

K.-B. Kim, D.-W. Kim, Y. Kim, J. Tang, N. Kirk, Y. Gan, B. Fang, J.-I. Park, Y. Zheng, K.-S. Park

This study identifies the WNT5A-RHOA axis as a critical driver of small-cell lung cancer, offering new therapeutic targets and insights into WNT signaling heterogeneity.

bioRxiv · Apr 14, 2022 · PreprintCancer Biology

Unique role and vulnerability of EP300 KIX domain in small-cell lung cancer

K.-B. Kim, A. Kabra, D.-W. Kim, Y. Xue, P.-C. Hou, Y. Zhou, L. Miranda, X. Shi, T. P. Bender, J. H. Bushweller, K.-S. Park

The paper identifies the EP300 KIX domain as a critical driver of SCLC and shows that targeting this domain can inhibit tumor growth.

bioRxiv · Jun 3, 2021 · PreprintCancer Biology

FGFR1 is critical for Rbl2 loss-driven tumor development and requires PLCG1 activation for continued growth of small cell lung cancer

K.-B. Kim, Y. Kim, D.-W. Kim, K.-S. Park

This study identifies FGFR1's role in SCLC development and growth, showing its dependency on Rbl2 loss and PLCG1 activation.

Cancer Research · Nov 13, 2020Peer-reviewedCancer Biology

Role of ischemic preconditioning in cardioprotective mechanisms of mCRP deposited myocardium in a rat model

E. N. Kim, J.-S. Choi, C. J. Kim, S. R. Kim, K.-B. Kim, S. J. Oh

This study evaluates how ischemic preconditioning (IPC) affects myocardial damage caused by mCRP deposition in a rat model of ischemia-reperfusion injury, finding reduced infarct size and mCRP deposition with IPC.

bioRxiv · May 13, 2020 · PreprintPathology

Fragmentation of Small-cell Lung Cancer Regulatory States in Heterotypic Microenvironments

D. Schaff, S. Singh, K.-B. Kim, M. Sutcliffe, K.-S. PARK, K. Janes

This study identifies regulatory state heterogeneity in small-cell lung cancer cells in vitro and in vivo, showing increased fragmentation in the liver and its prognostic relevance in human tumors.

bioRxiv · Mar 30, 2020Cancer Biology

A trans-eQTL network regulates osteoclast multinucleation and bone mass

M. Pereira, J.-H. Ko, J. Logan, H. Protheroe, K.-B. Kim, A. L. M. Tan, K.-S. Park, M. Rotival, E. Petretto, J. H. D. Bassett, G. R. Williams, J. Behmoaras

The paper identifies a trans-eQTL network (MMnet) that regulates osteoclast multinucleation and bone mass in mice and humans.

bioRxiv · Feb 13, 2020Cell Biology