Author

Kyla B. Buettner

Oklahoma Medical Research Foundation

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Ana J. Chucair‐ElliottiD· 2 shared Arlan G RichardsoniD· 2 shared David R. StanfordiD· 2 shared Michael B. StoutiD· 2 shared Michael J. BecksteadiD· 2 shared Sarah R. OcañasiD· 2 shared Victor A. AnsereiD· 2 shared Willard M. FreemaniD· 2 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Ana J. Chucair‐ElliottORCID

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Author profile →

2 papers

Recent·Most cited

A new epigenetic framework for DNA methylation, hydroxymethylation, and gene expression during brain aging.

Sarah R. Ocañas, Walker Hoolehan, Kevin D. Pham, Christian T. Wright, Kyla B. Buettner, Victor A. Ansere, Adeline H. Machalinski, David R. Stanford, Adam M. Kulpa, Hannah Ray, Collyn M. Kellogg, Derek M. Huffman, Arlan G Richardson, Michael B. Stout, Michael J. Beckstead, , Willard M. Freeman

The paper shows that cell identity and regulatory logic are preserved during brain aging, but cell-type-specific changes occur in DNA modifications and gene expression.

bioRxiv · Oct 21, 2026 · PreprintNeuroscience

Inducible cell-specific mouse models for paired epigenetic and transcriptomic studies of microglia and astroglia

Ana J. Chucair‐Elliott, Sarah R. Ocañas, David R. Stanford, Victor A. Ansere, Kyla B. Buettner, Hunter L. Porter, Nicole L. Eliason, Justin J. Reid, Amanda Lea Sharpe, Michael B. Stout, Michael J. Beckstead, Benjamin F. Miller, Arlan G Richardson, Willard M. Freeman

The paper introduces a NuTRAP method to isolate RNA and DNA from specific CNS cell types, revealing cell type-specific epigenetic and transcriptomic differences in microglia and astrocytes.

Communications Biology · Nov 19, 2020Peer-reviewedNeuroscience