Author

H. J. Shin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Microbiology· 2 Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Organism:mouse· 1 Organism:plant (other)· 1

Frequent Co-Authors

A. Biswas· 1 shared A. N. Engelman· 1 shared A. Natasha· 1 shared A. R. ANVIKAR· 1 shared B. Akosman· 1 shared B. K. NA· 1 shared B. Kim· 1 shared B. Ma· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperBiochemistry

A. Biswas

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Oligomeric HIV-1 Integrase Structures Reveal Functional Plasticity for Intasome Assembly and RNA Binding

T. Jing, Z. Shan, T. Dinh, A. Biswas, S. Jang, J. Greenwood, M. Li, Z. Zhang, G. Gray, H. J. Shin, B. Zhou, D. Passos, T. S. Strutzenberg, S. Aiyer, L. Andrade, , D. Lyumkis

This study determines cryo-EM structures of HIV-1 integrase tetramers and intasome hexadecamers, revealing structural plasticity and functional roles in viral integration and RNA binding.

bioRxiv · Jan 26, 2024 · PreprintBiochemistry

In vitro broad-spectrum antiviral activity of MIT-001, a mitochondria-targeted reactive oxygen species scavenger, against severe acute respiratory syndrome coronavirus 2 and multiple zoonotic viruses

T. Lim, S. Rajoriya, B. Kim, S. p. Prayitno, A. Natasha, J. Park, N. Y. Jang, H. Im, H. S. Shim, J. Yoo, J. W. Kim, E.-W. Lee, H. J. Shin, S. H. Kim, W.-K. Kim

This study evaluates MIT-001's antiviral activity against SARS-CoV-2 and zoonotic viruses in vitro, showing inhibition of viral replication and restoration of antioxidant gene expression.

bioRxiv · Jul 6, 2023 · PreprintMicrobiology

Ocular tropism of SARS-CoV-2 with retinal inflammation through neuronal invasion in animal models

G. U. Jeong, H.-J. Kwon, H. W. Moon, G. Y. Yoon, H. J. Shin, J. S. Chae, S.-J. Kim, I.-C. Lee, K.-D. Kim, D.-G. Ahn, S. Mahalingam, Y.-C. Kwon

This study investigates SARS-CoV-2 ocular tropism and neuroinvasion in animal models, showing virus spread to the brain and eyes via nerves and causing retinal inflammation.

bioRxiv · Apr 17, 2022 · PreprintMicrobiology

Cyclic constrained immunoreactive peptides from crucial P. falciparum proteins: potential implications in malaria diagnostics

K. VASHISHT, S. SRIVASTAVA, V. KUMARI, R. DAS, S. SHARMA, N. BHARDWAJ, A. R. ANVIKAR, T. S. KIM, B. K. NA, H. J. SHIN, K. C. PANDEY

The paper identifies three cyclic constrained peptides from P. falciparum proteins that show immunoreactivity and diagnostic potential in field-collected samples.

bioRxiv · Oct 11, 2021Biochemistry

Chitinase 3-like-1 is a Therapeutic Target That Mediates the Effects of Aging in COVID-19

S. Kamle, B. Ma, C. H. He, B. Akosman, Y. Zhou, C.-M. Lee, W. S. El-Deiry, K. Huntington, O. Liang, J. T. Machan, M.-J. Kang, H. J. Shin, E. Mizoguchi, C. G. Lee, J. A. Elias

This study identifies CHI3L1 as a key mediator of aging-related severity in COVID-19 by stimulating ACE2 and SPP expression, and shows it is a therapeutic target.

bioRxiv · Jan 5, 2021Immunology

Novel surface plasmon resonance biosensor that uses full-length Det7 phage tail protein for rapid and selective detection of Salmonella enterica serovar Typhimurium

H. J. Shin, W. K. Lim, S. H. Hyeon

This paper develops a SPR biosensor using Det7T protein to rapidly and selectively detect S. Typhimurium, showing specificity and effectiveness in spiked apple juice.

bioRxiv · Jul 11, 2019Bioengineering