L. Liu

This study analyzes the nutritional composition and transcriptome of early-stage Japanese eel larvae to understand their nutrient requirements and metabolic pathways.

This study shows that TLR7 signaling protects mice from lethal SARS-CoV-2 infection by enhancing antiviral responses and reducing inflammation.

This study shows that subsidiary cells and the PAN2 receptor are essential for stomatal closure in maize, with PAN2 having an additional role beyond subsidiary cell function.

This study identifies two antibodies that neutralize all SARS-CoV-2 variants by locking the spike protein in a down conformation, showing a novel mechanism and potential for prophylaxis.

This study examines Listeria species in beach sand, identifying hypervirulent isolates and their potential role in human listeriosis.

This study establishes and evaluates rat models of cervical spondylopathy with Yin deficiency syndrome through sleep deprivation and behavioral assessments.

The paper examines altered receptor specificities of H3N2 influenza viruses using NMR and computational methods to identify binding interactions with extended N-glycans.

This study identifies RCF1 as a key player in miRNA biogenesis and RNA splicing in Arabidopsis by showing its role in pri-miRNA processing and splicing defects in a mutant.

This study tracks microbial colonization in neonatal calves and identifies genetic links between microbes and host metabolites affecting health and growth.

This study shows that early microbial intervention in newborn calves reduces diarrhea and improves later milk production by altering gut microbiome composition and metabolite profiles.

This study investigates how calcitriol and cholesterol translocate through H. pylori lipid membranes and their effects on water permeability using molecular dynamics simulations.

The paper analyzes the receptor affinity and antibody evasion properties of SARS-CoV-2 BA.2.75 subvariants, identifying two evolutionary pathways and three mutations that influence their virological features.

This paper introduces an epigenetic clock based on stochastic DNA methylation changes in plants, enabling high-resolution temporal analysis of phylogenetic relationships.

This study identifies ZmPTOX1 as a key gene for carotenoid biosynthesis in maize kernels, showing that its disruption reduces carotenoid content while overexpression increases it, particularly beta-carotene.

This study identifies HIF2/ARNT as a protective axis in cardiac endothelial cells post-MI, preventing vascular leakage and inflammation through suppression of IL6.

This study develops a high-throughput assay to quantify SARS-CoV-2 spike-mediated cell-cell fusion and finds that it is more resistant to antibody inhibition than cell-free infection.

This study identifies RNA sensing and innate immunity in host embryos as a barrier to interspecies chimerism and shows that modifying host embryos can enhance human cell survival in chimeric embryos.

The paper reports structures of Las1-Grc3 complexes and identifies their role in pre-rRNA cleavage during ribosome biosynthesis.

The paper develops a high-throughput platform for screening functional neo-antigens and their specific TCRs using droplet microfluidics and DNA barcoding.

This study compares neutralizing antibody titers after bivalent and monovalent mRNA boosters and BA.5 breakthrough infection, finding no significant difference at one month but higher titers in breakthrough patients at three months.

This study shows that apolipoprotein E enhances herpes simplex virus 1 attachment, entry, and release by modifying its interactions with cell membranes.

This study annotates IGH germline genes in three bat species and analyzes the CDR3 repertoire of Rhinolophus affinis, revealing unique immunological features that may explain asymptomatic viral infections in bats.

The paper identifies the T813S mutation in the S2 subunit of SARS-CoV Spike protein enhances fusogenicity by improving TMPRSS2 cleavage, increasing viral replication.

This study investigates the relationship between breast cancer and gut microbiome by analyzing fecal samples from mice with induced breast tumors, finding changes in microbial composition and signaling pathways.

The paper identifies transcription factors driving distinct CD8+ T cell states and shows their impact on tumor control and immunotherapy.

This study develops a coevolutionary game model to show how cooperation and risk interact in collective-risk social dilemmas, finding that cooperation can be sustained through specific feedback mechanisms and initial conditions.

This paper uses machine learning on autofluorescence lifetime images to predict metabolic pathway usage in cancer cells, achieving 95% accuracy in distinguishing glycolytic and oxidative metabolism.

The paper identifies the abfA cluster as a key genetic factor for arabinan utilization in gut microbiota, showing its therapeutic potential for constipation through improved gut motility and metabolite production.

This paper introduces a compact microscope for label-free detection of nanometer-scale objects in non-laboratory settings, demonstrating its performance with nanoparticles and biological samples.

The paper identifies a host metabolic pathway essential for coronavirus replication and shows that inhibiting it with Propranolol has broad antiviral effects.