Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
41 papers
Recent·Most cited
J. A. Carozza, V. Boehnert, K. C. Nguyen, G. Skariah, K. E. Shaw, J. A. Brown, M. Rafat, R. von Eyben, E. E. Graves, J. S. Glenn, M. Smith, L. Li
The paper identifies extracellular 2’3’-cGAMP as an immunotransmitter released by cancer cells, regulated by ENPP1, and shows its therapeutic potential in tumor treatment.
bioRxiv · Oct 7, 2019Biochemistry
C. Wang, C. V. Forst, T.-w. Chou, A. Geber, M. Wang, W. Hamou, M. Smith, R. Sebra, B. Zhang, B. Zhou, E. Ghedin
This study uses single-cell RNA sequencing to analyze viral transcription and host responses in influenza-infected cells, revealing cell-to-cell variation driven by defective viral genomes.
bioRxiv · Aug 21, 2019Microbiology
O. Perovic, A. A. Yahaya, C. Viljoen, J.-B. Ndihokubwayo, M. Smith, S. O. Coulibaly, L. de Gouveia, C. J. Oxenford, S. B. F. Cognat, J. A. Frean
This study evaluates the effectiveness of an external quality assessment program for bacterial identification and antimicrobial susceptibility testing in African public health laboratories from 2011-2016, finding that while identification scores were generally acceptable, antimicrobial susceptibility testing performance was poor.
bioRxiv · Aug 20, 2019Microbiology
A. Ardalan, S. Uwumarenogie, M. Fish, S. Sowlati-Hashjin, M. Karttunen, M. Smith, M. Jelokhani-Niaraki
This study provides experimental and computational evidence that UCP2 self-assembles into stable tetramers in lipid bilayers, which are functional for proton transport and may regulate ATP synthesis.
bioRxiv · Jul 16, 2019 · PreprintBiophysics
R. Hoeven, J. Hughes, M. Amer, E. Wojcik, S. Tait, M. Faulkner, I. Yunus, S. Hardman, L. Johannissen, G.-Q. Chen, M. Smith, P. Jones, H. Toogood, N. Scrutton
This paper demonstrates the production of bio-LPG from waste volatile fatty acids using engineered microbes, offering a sustainable alternative to fossil fuels.
bioRxiv · May 17, 2019 · PreprintBioengineering
H. G. Hilton, N. D. Rubinstein, P. Janki, A. T. Ireland, N. Bernstein, K. M. Wright, D. Finkle, B. Martin-McNulty, M. Roy, M. Smith, D. M. Imai, V. Jojic, R. Buffenstein
This study uses single-cell transcriptomics to analyze the immune system of naked mole-rats, revealing unique features like a high myeloid-to-lymphoid ratio and absence of natural killer cells.
bioRxiv · Apr 4, 2019Immunology
C. Lehmann, D. Griffith, K. Simpson, M. Anderson, S. Archibald, D. Beerling, W. Bond, E. Denton, E. Edwards, E. Forrestel, D. Fox, D. Georges, W. Hoffmann, T. Kluyver, L. Mucina, , C. Osborne
The paper maps global grassy biomes and identifies key traits and lineages driving their distribution across climates.
bioRxiv · Mar 21, 2019 · PreprintEcology
G. Cuadra, M. Smith, J. M. Nelson, E. Loh, D. Palazzolo
This study examines the effects of flavorless e-cigarette aerosol and cigarette smoke on oral commensal streptococci survival and growth, finding that aerosol has a modest effect while smoke significantly reduces bacterial survival.
bioRxiv · Jan 24, 2019Microbiology
N. McNeer, J. Philip, H. Geiger, R. Ries, V.-P. Lavallee, M. Walsh, M. Shah, K. Arora, A.-K. Emde, N. Robine, T. A. Alonzo, E. A. Kolb, A. S. Gamis, M. Smith, D. S. Gerhard, , A. Kentsis
The paper identifies genetic mechanisms of primary chemotherapy resistance in pediatric AML through whole-genome and transcriptome sequencing of treatment-failure cases.
bioRxiv · Nov 26, 2018Cancer Biology
H. Gao, B. Murugesan, J. Hossbach, S. Evans, M. Stark, M. Smith
This study identifies integrating vectors for Amycolatopsis marina using TG1 and R4 integrases, enabling site-specific genome integration in rare Actinomycetes.
bioRxiv · Nov 22, 2018Microbiology
J. Morgan, M. Smith, M. T. Mc Auley, J. E. Salcedo-Sora
This study shows that disrupting folate metabolism reduces the formation of antibiotic persisters in bacteria during exponential growth.
bioRxiv · May 31, 2018Microbiology