Author

Manuel C. Marzin

Amsterdam UMC Location Vrije Universiteit Amsterdam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:database / resource· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1

Frequent Co-Authors

Erik NutmaiD· 2 shared Sandra AmoriD· 2 shared Alexandra E. M. PhillipsiD· 1 shared Amy M. SmithiD· 1 shared Anna M. BarroniD· 1 shared Anna WilliamsiD· 1 shared Aurélien M. BadinaiD· 1 shared Benjamin B. TournieriD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersNeuroscience

Erik NutmaORCID

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2 papers

Recent·Most cited

Single nuclei RNAseq stratifies multiple sclerosis patients into distinct white matter glia responses

Will Macnair, Daniela Calini, Eneritz Agirre, Julien Bryois, Sarah Jäkel, Rebecca Sherrard Smith, Petra Kukanja, Nadine Stokar‐Regenscheit, Virginie Ott, Lynette C. Foo, Ludovic Collin, Sven Schippling, Eduard Urich, Erik Nutma, Manuel C. Marzin, , Dheeraj Malhotra

The paper uses single nuclei RNAseq to identify distinct glial gene expression patterns in MS patients, revealing subgroup-specific pathological processes and suggesting precision medicine approaches.

Neuron · Dec 20, 2024Peer-reviewedNeuroscience

Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases

Erik Nutma, Nurun Nahar Fancy, Maria Weinert, Stergios Tsartsalis, Manuel C. Marzin, Robert C. J. Muirhead, Irene N. Falk, Marjolein Breur, Joy de Bruin, David Hollaus, Robin Pieterman, Jasper J. Anink, David Story, Siddharthan Chandran, Jiabin Tang, , David R. Owen

The paper shows TSPO expression increases in activated microglia in rodent models but not in human neurodegenerative diseases, indicating species-specific differences in TSPO function.

Nature Communications · Aug 28, 2023Peer-reviewedNeuroscience