Author

Nicholas Macoretta

University of Rochester

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Developmental Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:DNA methylation· 3 Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Research Focus:benchmarking· 1 Organism:C. elegans· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Amin HaghaniiD· 2 shared Caesar Z. LiiD· 2 shared Chris G. FaulkesiD· 2 shared Joseph Alan ZolleriD· 2 shared Joshua ZhangiD· 2 shared Julia AblaevaiD· 2 shared Stephan EmmrichiD· 2 shared Vera A. GorbunovaiD· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersDevelopmental Biology

Amin HaghaniORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Universal DNA methylation age across mammalian tissues

Ake Tzu-Hui Lu, Zhe Fei, Amin Haghani, Todd R. Robeck, Joseph Alan Zoller, Caesar Z. Li, Robert Lowe, Qi Jiang Yan, Joshua Zhang, H. Vu, Julia Ablaeva, Victoria A. Acosta-Rodríguez, Danielle M. Adams, Javier Almunia, Ajoy Aloysius, , June Mergl

The paper develops universal epigenetic clocks that accurately estimate age across mammalian tissues using DNA methylation data from 185 species.

Nature Aging · Aug 10, 2023Peer-reviewedDevelopmental Biology

Homeodomain-interacting protein kinase maintains neuronal homeostasis during normal Caenorhabditis elegans aging and systemically regulates longevity from serotonergic and GABAergic neurons

María I. Lázaro‐Peña, Adam B. Cornwell, Carlos A. Díaz-Balzac, Ritika Das, Zachary C. Ward, Nicholas Macoretta, Juilee Thakar, Andrew V. Samuelson

This study identifies HPK-1 as a neuronal transcriptional regulator that maintains proteostasis and extends longevity in C. elegans by modulating serotonergic and GABAergic pathways.

eLife · Jun 20, 2023Peer-reviewedGenetics

DNA methylation clocks show slower progression of aging in naked mole-rat queens

Steve Horvath, Amin Haghani, Nicholas Macoretta, Julia Ablaeva, Joseph Alan Zoller, Caesar Z. Li, Joshua Zhang, Masaki Takasugi, Yang Zhao, Elena B. Rydkina, Zhihui Zhang, Stephan Emmrich, Ken Raj, Andrei Seluanov, Chris G. Faulkes, Vera Gorbunova

This study develops DNA methylation clocks for naked mole-rats and finds that queens age more slowly than non-breeders, suggesting a link between reproductive status and epigenetic aging.

bioRxiv · Mar 15, 2021 · PreprintDevelopmental Biology