P. Janmey

Extracellular Vimentin is a Damage-Associated Molecular Pattern Protein Serving as an Agonist of TLR4 in Human Neutrophils

This study shows extracellular vimentin and its citrullinated form activate TLR4 on human neutrophils, influencing migration, NET formation, and pathogen phagocytosis differently.

Glomerular Elastic Modulus and Gene Expression PatternsDefine Two Phases of Alport Nephropathy

This study identifies early glomerular changes and gene expression patterns in Alport syndrome, showing ER stress and four genes as key drivers of disease before proteinuria, and highlights potential therapeutic targets.

Large polyacrylamide hydrogels for large-batch cell culture and mechanobiological studies

This paper introduces a method to prepare large-batch polyacrylamide hydrogels with tunable stiffness for mechanobiological studies and cell culture.

Extracellular vimentin is sufficient to promote cell attachment, spreading, and motility by a mechanism involving N-acetyl glucosamine-containing structures

This study shows extracellular vimentin promotes cell attachment, spreading, and motility via N-acetyl glucosamine-containing structures, identifying a novel adhesion mechanism.

Electrical Stimulation of Human Mesenchymal Stem Cells on Conductive Chitosan-Polyaniline Substrates Promotes Neural Priming

This study shows that electrical stimulation of hMSCs on soft conductive CS-g-PANI substrates increases neural markers and decreases glial markers, suggesting a neural-like phenotype.

A study of hyperelastic continuum models for isotropic athermal fibrous networks

This study evaluates four hyperelastic models for isotropic athermal fibrous networks, finding that affine and three-chain models accurately capture mechanical behavior under tension and shear, while others fail.

Vimentin Intermediate Filaments Can Enhance or Abate Active Cellular Forces in a Microenvironmental Stiffness-Dependent Manner

This study shows vimentin intermediate filaments modulate cell-generated forces depending on microenvironment stiffness, increasing forces on stiff matrices and decreasing them on soft matrices.

The Correlation Between Cell and Nucleus Size is Explained by an Eukaryotic Cell Growth Model

The paper develops a computational model of cell growth and proteome increase to explain the correlation between cell and nuclear volume, showing that transport rates and ribosome dynamics influence growth and volume ratios.

Synergistic effects of conductivity and cell-imprinted topography of chitosan-polyaniline based scaffolds for neural differentiation of adipose-derived stem cells

This study shows that conductive chitosan-polyaniline scaffolds with cell-imprinted topography significantly enhance neural differentiation of rat adipose-derived stem cells.

Vimentin protects the structural integrity of the nucleus and suppresses nuclear damage caused by large deformations

This study shows that vimentin intermediate filaments protect the nucleus from damage during cell migration by maintaining its shape and mechanical integrity.