Author

A. Vahabikashi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

J. J. Fredberg· 2 shared M. Johnson· 2 shared R. D. Goldman· 2 shared S. A. Adam· 2 shared W. D. Stamer· 2 shared A. E. Patteson· 1 shared A. Goldman· 1 shared C. Y. Park· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersBiophysics

J. J. Fredberg

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Author profile →

4 papers

Recent·Most cited

Surface Engineering of FLT4-Targeted Nanocarriers Enhances Cell-Softening Glaucoma Therapy

M. P. Vincent, T. Stack, A. Vahabikashi, G. Li, K. M. Perkumas, R. Ren, H. Gong, W. D. Stamer, M. Johnson, E. A. Scott

This paper develops FLT4-targeted nanocarriers for glaucoma therapy, showing improved IOP reduction and targeted delivery to Schlemms canal cells.

ACS Applied Materials & Interfaces · Jul 7, 2021Peer-reviewedBioengineering

Nuclear lamin isoforms differentially contribute to LINC complex-dependent nucleocytoskeletal coupling and whole cell mechanics

A. Vahabikashi, S. Sivagurunathan, F. A. S. Nicdao, Y. L. Han, C. Y. Park, X. Wong, J. R. Tran, G. G. Gundersen, K. Reddy, G. G. Luxton, M. Guo, J. J. Fredberg, Y. Zheng, S. A. Adam, R. D. Goldman

This study shows that different nuclear lamin isoforms modulate cell and nuclear mechanics by affecting LINC complex stability and heterochromatin structure in mouse embryonic fibroblasts.

bioRxiv · May 12, 2021Biophysics

Vimentin protects the structural integrity of the nucleus and suppresses nuclear damage caused by large deformations

A. E. Patteson, A. Vahabikashi, K. Pogoda, S. A. Adam, A. Goldman, R. Goldman, P. Janmey

This study shows that vimentin intermediate filaments protect the nucleus from damage during cell migration by maintaining its shape and mechanical integrity.

bioRxiv · Mar 3, 2019Cell Biology

Probe Sensitivity to Cortical versus Intracellular Cytoskeletal Network Stiffness

A. Vahabikashi, C. Young Park, K. Perkumas, Z. Zhang, E. K. Deurloo, H. Wu, D. A. Weitz, W. D. Stamer, R. D. Goldman, J. J. Fredberg, M. Johnson

The paper compares the sensitivity of four probe technologies to measure biomechanical properties of different cellular regions in two cell types under various perturbations.

bioRxiv · Oct 16, 2018Biophysics