P. Schulze-Lefert

A barley MLA receptor is targeted by a non-ribosomal peptide effector of the necrotrophic spot blotch fungus for disease susceptibility

This study identifies Scs6, a barley gene required for susceptibility to the necrotrophic fungus Bipolaris sorokiniana, and shows it is targeted by a non-ribosomal peptide effector.

Commensal lifestyle regulated by a negative feedback loop between Arabidopsis ROS and the bacterial T2SS

The paper shows that Arabidopsis ROS inhibits the T2SS of commensal bacteria, preventing their harmful effects and promoting plant health.

Structural polymorphisms within a common powdery mildew effector scaffold as a driver of co-evolution with cereal immune receptors

This study reports the structures of powdery mildew effector proteins and shows how structural polymorphisms within a common scaffold drive co-evolution with cereal immune receptors.

Simultaneous tracking of near-isogenic bacterial strains in synthetic Arabidopsis microbiota by chromosomally-integrated barcodes

This paper introduces MoBacTags to track near-isogenic bacterial strains in synthetic Arabidopsis microbiota, revealing distinct roles of pqqF and cyoB in community establishment.

A dominant-negative avirulence effector of the barley powdery mildew fungus provides mechanistic insight to barley MLA immune receptor activation

The paper shows that a modified powdery mildew effector, AVRA13-V2, escapes recognition by the barley MLA13 receptor and contributes to resistance breakdown.

Targeted gene deletion with SpCas9 and multiple guide RNAs in Arabidopsis thaliana: four are better than two

This study shows that using two pairs of guide RNAs with SpCas9 increases chromosomal deletion frequency in Arabidopsis, and TREX2 co-expression enhances deletion size without increasing deletion frequency.

A wheat resistosome defines common principles of immune receptor channels

This study reports the cryo-EM structure of the wheat CNL Sr35 resistosome and shows its structural and functional conservation with the Arabidopsis ZAR1 resistosome.

TIR domains of plant immune receptors are 2',3'-cAMP/cGMP synthetases mediating cell death

A fungal powdery mildew pathogen induces extensive local and marginal systemic changes in the Arabidopsis thaliana microbiota

This study investigates how powdery mildew infection affects microbial communities in Arabidopsis thaliana, showing local and marginal systemic changes in foliar but not root-associated bacteria.

Differential impact of plant secondary metabolites on the soil microbiota

The paper examines how three plant metabolites affect soil bacterial communities, finding distinct impacts on taxa abundance and diversity.

Host preference and invasiveness of commensals in the Lotus and Arabidopsis root microbiota

The paper investigates host preference and invasiveness of commensal bacteria in the root microbiota of Lotus and Arabidopsis, showing host-specific adaptation and competitive advantages.

Spatially Restricted Immune Responses Allow for Root Meristematic Activity During Bacterial Colonisation

The paper shows that spatially restricted immune responses in plant roots allow meristematic activity during bacterial colonization by distinguishing cell-autonomous and non-cell autonomous responses.

Gene expression evolution in pattern-triggered immunity within Arabidopsis thaliana and across Brassicaceae species

The paper identifies genes under purifying selection and species-specific expression signatures in PTI responses across Brassicaceae species using comparative transcriptomics.

Two Receptor-Like Kinases Required For Arabidopsis Endodermal Root Organisation Shape The Rhizosphere Microbiome

This study identifies ERK1 and RBK1 as key regulators of Casparian Strip formation in Arabidopsis, which in turn influences rhizosphere microbiome composition.

Lotus japonicus symbiosis genes impact microbial interactions between symbionts and multikingdom commensal communities

This study examines how symbiosis genes in Lotus japonicus shape bacterial and fungal root-associated communities in natural soil.

Plant mixed lineage kinase domain-like proteins limit biotrophic pathogen growth

The paper identifies a plant MLKL protein family structurally similar to vertebrate MLKL, which provides immunity against pathogens without inducing cell death.

Root microbiota assembly and adaptive differentiation among European Arabidopsis populations

The paper examines root microbiota variation in Arabidopsis thaliana across Europe, finding that climate drives adaptation more than soil conditions or microbial composition.

Arabidopsis phytochelatin synthase 1, but not phytochelatin synthesis, functions in extracellular defense against multiple fungal pathogens

This study identifies PCS1 as a moonlighting protein involved in extracellular defense against fungal pathogens in Arabidopsis, independent of its known role in heavy metal detoxification.

Plant-derived coumarins shape the composition of an Arabidopsis synthetic root microbiome

The paper investigates how coumarins from Arabidopsis roots influence the microbiome under iron deficiency, showing they inhibit a Pseudomonas strain via redox mechanisms.

Microbial interkingdom interactions in roots promote Arabidopsis survival

The paper investigates microbial interactions in Arabidopsis roots, showing bacterial microbiota protect plants from filamentous eukaryotes and maintain microbial balance.

Incomplete reprogramming of cell-specific epigenetic marks during asexual reproduction leads to heritable phenotypic variation in plants